Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25724576 | 0.96 | PARP10 (0.46) | PARP10PRSS1PLAUPLA2G2AF2 | |
| SCHEMBL5036891 | 0.90 | PLA2G2A (0.46) | PARP10PRSS1PLA2G2AF2PRSS2 | |
| SCHEMBL2188463 | 0.84 | PLA2G2A (0.61) | PLAUPLA2G2ATAAR1TSHRKMT2A | |
| SCHEMBL14536663 | 0.82 | L3MBTL1 (0.48) | PLAUPLA2G2ATAAR1KMT2AALDH1A1 | |
| SCHEMBL6836738 | 0.82 | PLA2G2A (0.54) | PARP10PRSS1PLA2G2AF2PRSS2 | |
| SCHEMBL19732841 | 0.82 | PARP1 (0.59) | PARP10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL17414620 | 0.81 | PLA2G2A (0.62) | PARP10PLA2G2ATSHR | |
| SCHEMBL6122034 | 0.80 | PARP10 (0.70) | PARP10PRSS1TAAR1PARP1KMT2A | |
| SCHEMBL13411802 | 0.80 | TAAR1 (0.59) | PLAUPLA2G2ATAAR1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL12502964 | 0.78 | PARP10 (0.68) | PARP10PRSS1TAAR1PARP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111236-A2 | NOVEL CASCADE POLYMER COMPLEXES, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THE SAME | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-10-28 | — | — | EP | claimed |
| US-20080213187-A1 | NOVEL CASCADE POLYMER COMPLEXES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | EPIX PHARMACEUTICALS, INC. | 2008-09-04 | — | — | US | claimed |
| WO-2008087017-A2 | NOVEL CASCADE POLYMER COMPLEXES, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THE SAME | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-24 | — | — | WO | claimed |
| EP-2111236-A2 | NOVEL CASCADE POLYMER COMPLEXES, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THE SAME | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-10-28 | — | — | EP | disclosed |
| US-20080213187-A1 | NOVEL CASCADE POLYMER COMPLEXES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | EPIX PHARMACEUTICALS, INC. | 2008-09-04 | — | — | US | disclosed |
| WO-2008087017-A2 | NOVEL CASCADE POLYMER COMPLEXES, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THE SAME | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080213187-A1 | NOVEL CASCADE POLYMER COMPLEXES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PGF, F13A1, F11 | PARP10 120/4885PRSS1 2296/4885PLAU 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.