Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11945827 | 0.86 | OPRM1 (0.54) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL32686822 | 0.84 | CTSL (0.45) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL20284996 | 0.84 | OPRM1 (0.51) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL22111662 | 0.83 | OPRM1 (0.48) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL25183679 | 0.83 | CTSL (0.47) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL22594119 | 0.82 | OPRM1 (0.53) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL19388482 | 0.81 | OPRM1 (0.60) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL25268815 | 0.81 | CTSL (0.54) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL25269671 | 0.81 | CTSL (0.43) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL26775766 | 0.81 | CTSL (0.49) | CTSLCTSBCTSKOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2103598-A1 | Fluorinated cycloalkyl-derived benzoylguanidine, method for producing same, use of same as medicine and medicine containing same | Sanofi-Aventis Deutschland GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| EP-1515947-B1 | FLUORINATED CYCLOALKYL-DERIVATISED BENZOYLGUANIDINES AND THEIR USE AS A MEDICAMENT | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-09-09 | — | — | EP | disclosed |
| US-6878748-B2 | Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-04-12 | — | — | US | disclosed |
| EP-1515947-A1 | FLUORINATED CYCLOALKYL-DERIVATISED BENZOYLGUANIDINES AND THEIR USE AS A MEDICAMENT | Aventis Pharma Deutschland GmbH (DE) | 2005-03-23 | — | — | EP | disclosed |
| US-20040048930-A1 | Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-03-11 | — | — | US | disclosed |
| WO-2003106410-A1 | FLUORINATED CYCLOALKYL-DERIVATISED BENZOYLGUANIDINES AND THEIR USE AS A MEDICAMENT | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048930-A1 | Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them | FABP3, TNNI3, TNNT2 | CTSL 1804/4885CTSB 762/4885CTSK 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.