Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | GFER | P55789 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23347931 | 0.84 | MAPT (0.77) | MAPTALDH1A1GFERGAALMNA | |
| SCHEMBL7043679 | 0.84 | MAPT (0.77) | MAPTALDH1A1GFERGAALMNA | |
| SCHEMBL6151120 | 0.84 | MAPT (0.77) | MAPTALDH1A1GFERGAALMNA | |
| SCHEMBL13159173 | 0.78 | MAPT (0.63) | MAPTALDH1A1GFERGAALMNA | |
| SCHEMBL20013105 | 0.78 | MAPT (0.63) | MAPTALDH1A1GFERGAALMNA | |
| Hydrochloric Acid SCHEMBL5169602 | 0.76 | MAPT (0.83) | MAPTALDH1A1GFERGAALMNA | |
| SCHEMBL12952701 | 0.76 | MAPT (0.65) | MAPTALDH1A1GFERGAALMNA | |
| SCHEMBL1858354 | 0.75 | ALDH1A1 (0.82) | MAPTALDH1A1GFERGAALMNA | |
| SCHEMBL33852 | 0.75 | ALDH1A1 (0.91) | MAPTALDH1A1GFERGAALMNA | |
| SCHEMBL19391229 | 0.75 | HRH3 (0.40) | MAPTALDH1A1GFERGAAADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2017-09-27 | — | — | EP | disclosed |