Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.91 |
| ▸ | MAPT | P10636 | 9/20 | 0.91 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.91 |
| ▸ | GAA | P10253 | 4/20 | 0.91 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.91 |
| ▸ | HTT | P42858 | 3/20 | 0.91 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.91 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.91 |
| ▸ | MEN1 | O00255 | 2/20 | 0.91 |
| ▸ | POLB | P06746 | 2/20 | 0.91 |
| ▸ | NPC1 | O15118 | 1/20 | 0.91 |
| ▸ | USP2 | O75604 | 1/20 | 0.91 |
| ▸ | TP53 | P04637 | 1/20 | 0.91 |
| ▸ | THRB | P10828 | 1/20 | 0.91 |
| ▸ | RECQL | P46063 | 1/20 | 0.91 |
| ▸ | RAB9A | P51151 | 1/20 | 0.91 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.91 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.91 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | GFER | P55789 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608042 | 0.97 | ALDH1A1 (0.95) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL1986101 | 0.97 | ALDH1A1 (0.95) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL156355 | 0.97 | ALDH1A1 (0.95) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| Hydrochloric Acid SCHEMBL1153999 | 0.97 | ALDH1A1 (0.95) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| Hydrochloric Acid SCHEMBL9014036 | 0.95 | ALDH1A1 (1.00) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL1858354 | 0.95 | ALDH1A1 (0.82) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL7128309 | 0.93 | ALDH1A1 (0.79) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL112440 | 0.92 | MAPT (0.78) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL7130594 | 0.91 | ALDH1A1 (0.83) | ALDH1A1MAPTL3MBTL1GAAKDM4E | |
| Hydrochloric Acid SCHEMBL5169602 | 0.90 | MAPT (0.83) | ALDH1A1MAPTL3MBTL1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2530 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768862-A | Indole pyrazole compound as well as preparation method and application thereof | 郑州大学 | 2023-09-19 | — | — | CN | claimed |
| US-11555017-B2 | Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres | L'OREAL (FR) | 2023-01-17 | — | — | US | claimed |
| US-20200392088-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2020-12-17 | — | — | US | claimed |
| EP-3638200-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING AT LEAST ONE BLUE, PURPLE OR GREEN DYE AND AT LEAST ONE DISULFIDE, THIOL OR PROTECTED THIOL FLUORESCENT DYE | L'Oreal (FR) | 2020-04-22 | — | — | EP | claimed |
| EP-3464247-B1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | OREAL (FR) | 2020-03-11 | — | — | EP | claimed |
| EP-3464247-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'Oréal (FR) | 2019-04-10 | — | — | EP | claimed |
| WO-2018229296-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING AT LEAST ONE BLUE, PURPLE OR GREEN DYE AND AT LEAST ONE DISULFIDE, THIOL OR PROTECTED THIOL FLUORESCENT DYE | L'OREAL (FR) | 2018-12-20 | — | — | WO | claimed |
| WO-2017202884-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2017-11-30 | — | — | WO | claimed |
| EP-2611797-B1 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | HANMI SCIENCE CO LTD (KR) | 2016-12-28 | — | — | EP | claimed |
| US-8835458-B2 | Quinoline or quinazoline derivatives with apoptosis inducing activity on cells | HANMI SCIENCE CO., LTD (KR) | 2014-09-16 | — | — | US | claimed |
| US-20020020029-A1 | Composition for the oxidation dyeing of keratinous fibers comprising at least one 1-(4-aminophenyl)pyrrolidine oxidation dye and at least one enzymatic oxidizing system, and dyeing methods | L'OREAL S.A. (FR) | 2002-02-21 | — | — | US | claimed |
| US-6342079-B1 | 1-(2,5-DIPHENYL)ETHANOL FOR HAIR DYES | BRISTOL-MYERS SQUIBB COMPANY | 2002-01-29 | — | — | US | claimed |
| EP-1149575-A1 | Oxidative dyeing composition for keratin fibres comprising 1-(4-aminophenyl)-pyrrolidine and a particular direct dye | L'OREAL (FR) | 2001-10-31 | — | — | EP | claimed |
| EP-1149576-A1 | Oxidative dyeing composition for keratinic fibres comprising 1-(4-aminophenyl)pyrrolidine and a sugar-based polymer | L'OREAL (FR) | 2001-10-31 | — | — | EP | claimed |
| EP-1149577-A1 | Oxidative dyeing composition for keratinic fibres comprising 1-aminophenyl-pyrroilidine and a cationic polymer | L'OREAL (FR) | 2001-10-31 | — | — | EP | claimed |
| EP-1147763-A1 | Oxidative dyeing composition for keratinic fibres containing 1-(4-aminophenyl)-pyrrolidine and an enzymatic oxidation system | L'OREAL (FR) | 2001-10-24 | — | — | EP | claimed |
| WO-2001054656-A1 | NOVEL PRIMARY INTERMEDIATE FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2001-08-02 | — | — | WO | claimed |
| EP-1120105-A2 | 1-(2,5-diaminophenyl)ethanol and its use in oxidative hair dyeing | Bristol-Myers Squibb Company (US) | 2001-08-01 | — | — | EP | claimed |
| EP-0891765-A2 | Oxidative hair dye compositions | Bristol-Myers Squibb Company (US) | 1999-01-20 | — | — | EP | claimed |
| US-5851237-A | Oxidative hair dye compositions and methods containing 1--(4-aminophenyl) pyrrolidines | NOXELL CORPORATION | 1998-12-22 | — | — | US | claimed |