Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 7/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 6/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 6/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 6/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461656 | 0.82 | GRIN2D (0.49) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL7458501 | 0.80 | GRIN2D (0.50) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL11637175 | 0.79 | GRIN1 (0.47) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL6003457 | 0.72 | PKM (0.47) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL7458749 | 0.71 | GRIN2D (0.49) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Hydrochloric Acid SCHEMBL27688881 | 0.71 | LMNA (0.46) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL12130587 | 0.70 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL9914296 | 0.70 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL8720366 | 0.70 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL12132159 | 0.70 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331495-A1 | PROCESS FOR MANUFACTURING ADAMANTANE DERIVATIVES WITH HIGH YIELD | Merz Pharma GmbH & Co. KGaA (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010015415-A1 | PROCESS FOR MANUFACTURING ADAMANTANE DERIVATIVES WITH HIGH YIELD | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-02-11 | — | — | WO | disclosed |