SCHEMBL4777402

SCHEMBL4777402

Clc1cccnc1-c1[c][nH]nc1Cl

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
HTT P42858 1/20 0.34
CNR2 P34972 1/20 0.33
S100A4 P26447 1/20 0.33
CDC25B P30305 1/20 0.33
NFE2L2 Q16236 2/20 0.32
ADRA2A P08913 1/20 0.31
ADRA2C P18825 1/20 0.31
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
RPS6KA5 O75582 1/20 0.31
PTPN11 Q06124 1/20 0.30
RORB Q92753 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5313096 0.83 DPP4 (0.33) DPP4SMN1; SMN2HTTCNR2S100A4
SCHEMBL5316789 0.80 TRPV1 (0.36) DPP4CNR2
SCHEMBL3633771 0.80 PTPN11 (0.36) DPP4CNR2RPS6KA5PTPN11
SCHEMBL5313166 0.80 CNR2 (0.36) SMN1; SMN2CNR2
SCHEMBL1939521 0.76 TRPV1 (0.32)
SCHEMBL1939427 0.74 NFE2L2 (0.33) S100A4CDC25BNFE2L2LMNA
SCHEMBL3632381 0.74 TRPV1 (0.33) DPP4
SCHEMBL1939367 0.73 AXL (0.34) DPP4CNR2S100A4CDC25BRPS6KA5
SCHEMBL2306238 0.72 DPP4 (0.48) DPP4CNR2S100A4CDC25BADRA2A
SCHEMBL8688609 0.70 DPP4 (0.47) DPP4CNR2S100A4CDC25BADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed