Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777402 | 0.80 | DPP4 (0.35) | PTPN11DPP4CNR2RPS6KA5 | |
| SCHEMBL5313096 | 0.77 | DPP4 (0.33) | DPP4CNR2METAP2 | |
| SCHEMBL5316789 | 0.77 | TRPV1 (0.36) | DPP4CNR2 | |
| SCHEMBL1939521 | 0.73 | TRPV1 (0.32) | — | |
| SCHEMBL3632381 | 0.71 | TRPV1 (0.33) | DPP4METAP2KCNH2GRM4 | |
| SCHEMBL1939427 | 0.71 | NFE2L2 (0.33) | GRM4 | |
| SCHEMBL3632343 | 0.71 | PTPN11 (0.38) | PTPN11DPP4LIMK1CNR2GRM4 | |
| SCHEMBL4455152 | 0.69 | — | — | |
| SCHEMBL1939367 | 0.68 | AXL (0.34) | DPP4CNR2RPS6KA5 | |
| SCHEMBL4637594 | 0.68 | DPP4 (0.34) | PTPN11DPP4LIMK1CNR2GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144898-A2 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008130021-A2 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-30 | — | — | WO | disclosed |