SCHEMBL19398457

SCHEMBL19398457

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nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 2/20 0.65
LGALS3 P17931 2/20 0.65
LGALS4 P56470 2/20 0.65
MAPK1 P28482 1/20 0.53
IGF2R P11717 2/20 0.48
CD209 Q9NNX6 2/20 0.48
IFNG P01579 1/20 0.47
FGF1 P05230 1/20 0.47
FGF2 P09038 1/20 0.47
BMP2 P12643 1/20 0.47
VEGFA P15692 1/20 0.47
SFRP1 Q8N474 1/20 0.47
BDNF P23560 2/20 0.45
PTN P21246 1/20 0.45
MDK P21741 1/20 0.45
SIGLEC7 Q9Y286 3/20 0.44
ENGASE Q8NFI3 1/20 0.44
CD69 Q07108 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19404388 1.00 LGALS8 (0.65) LGALS8LGALS3LGALS4MAPK1IGF2R
SCHEMBL19404390 1.00 LGALS8 (0.65) LGALS8LGALS3LGALS4MAPK1IGF2R
SCHEMBL15482021 0.98 LGALS8 (0.67) LGALS8LGALS3LGALS4MAPK1IGF2R
SCHEMBL18011604 0.98 LGALS8 (0.67) LGALS8LGALS3LGALS4MAPK1IGF2R
SCHEMBL13541646 0.98 LGALS8 (0.67) LGALS8LGALS3LGALS4MAPK1IGF2R
SCHEMBL18608298 0.98 LGALS8 (0.67) LGALS8LGALS3LGALS4MAPK1IGF2R
SCHEMBL18620664 0.98 LGALS8 (0.67) LGALS8LGALS3LGALS4MAPK1IGF2R
SCHEMBL19404689 0.97 LGALS8 (0.61) LGALS8LGALS3LGALS4MAPK1IGF2R
SCHEMBL13541636 0.96 LGALS8 (0.60) LGALS8LGALS3LGALS4MAPK1IGF2R
SCHEMBL22180491 0.96 LGALS8 (0.60) LGALS8LGALS3LGALS4MAPK1IGF2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170275389-A1 NOVEL GLYCAN CONJUGATES AND USE THEREOF ACADEMIA SINICA (TW) 2017-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170275389-A1 NOVEL GLYCAN CONJUGATES AND USE THEREOF STT3B, ST3GAL3, FUT6 LGALS8 28/4885LGALS3 43/4885LGALS4 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.