SCHEMBL1939999

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12541394	0.90	ITK (0.42)	MAPK1ITKEGFRBRD4MAPT
	SCHEMBL1939342	0.79	SYK (0.55)	SYKMAPK1HTTMAPTPPARG
	SCHEMBL12541550	0.78	JAK1 (0.45)	MAPK1ITKEGFRBRD4MAPT
	SCHEMBL1939834	0.77	SYK (0.45)	SYKMAPK1HTTMAPTPPARG
	SCHEMBL1298740	0.77	TP53 (0.56)	SYKMAPK1HTTMAPTPOLB
	SCHEMBL5887141	0.76	SYK (0.48)	SYKMAPK1HTTEGFRMAPT
	SCHEMBL1988039	0.75	SYK (0.42)	SYKMAPK1ITKEGFRBRD4
	SCHEMBL27791753	0.72	CA1 (0.49)	MAPTATMIDO1POLBNPSR1
	SCHEMBL31156800	0.71	BRD4 (0.44)	SYKITKEGFRBRD4POLB
	SCHEMBL25809430	0.71	BRD4 (0.44)	SYKITKEGFRBRD4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.