Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MAOB | P27338 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GPR183 | P32249 | 2/20 | 0.54 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.54 |
| ▸ | ITGAL | P20701 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19400203 | 0.89 | ALDH1A1 (0.69) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19400202 | 0.88 | MEN1 (0.73) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19400200 | 0.87 | ALDH1A1 (0.69) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16599446 | 0.83 | GPR183 (0.78) | MEN1KMT2ANPC1RAB9AGPR183 | |
| SCHEMBL16599445 | 0.83 | GPR183 (0.78) | MEN1KMT2ANPC1RAB9AGPR183 | |
| SCHEMBL19412472 | 0.82 | GPR183 (0.65) | MEN1KMT2AGPR183 | |
| SCHEMBL19400208 | 0.82 | GPR183 (0.73) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17340485 | 0.80 | MAOB (0.67) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29817180 | 0.79 | LMNA (0.70) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8912670 | 0.78 | ALDH1A1 (0.73) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776979-B2 | EBI2 modulators | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2017-10-03 | — | — | US | claimed |