Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16872904 | 0.88 | ALDH1A1 (0.65) | GAAALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL16872926 | 0.84 | ALDH1A1 (0.62) | GAAALDH1A1KMT2AKDM4EHSD17B10 | |
| SCHEMBL19400400 | 0.82 | ALDH1A1 (0.65) | GAAALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL16872917 | 0.82 | SMN1; SMN2 (0.73) | GAAALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL16872889 | 0.82 | KMT2A (0.53) | GAAALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL16872895 | 0.81 | ALDH1A1 (0.67) | GAAALDH1A1KMT2AKDM4EHSD17B10 | |
| SCHEMBL15506189 | 0.79 | GAA (0.65) | GAAALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL16872912 | 0.75 | SMN1; SMN2 (0.70) | GAAALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL16872923 | 0.74 | ALDH1A1 (0.65) | GAAALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL16872898 | 0.74 | ALDH1A1 (0.80) | GAAALDH1A1RECQLKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348295-A1 | SMALL MOLECULE INHIBITORS OF VIRAL PROTEIN INTERACTIONS WITH HUMAN T-RNA | SIRGA ADVANCED BIOPHARMA INC (US) | 2017-12-07 | — | — | US | disclosed |
| US-9775835-B2 | Small molecule inhibitors of viral protein interactions with human t-RNA | SIRGA ADVANCED BIOPHARMA, INC. (US) | 2017-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348295-A1 | SMALL MOLECULE INHIBITORS OF VIRAL PROTEIN INTERACTIONS WITH HUMAN T-RNA | NSUN3, TARBP1, TRDMT1 | GAA 2138/4885ALDH1A1 4756/4885RECQL 969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.