Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.80 |
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19665251 | 0.89 | MPO (0.67) | ALDH1A1RECQLGAAMEN1KMT2A | |
| SCHEMBL15613189 | 0.89 | ALDH1A1 (1.00) | ALDH1A1RECQLGAAMEN1KMT2A | |
| SCHEMBL15506189 | 0.77 | GAA (0.65) | ALDH1A1RECQLGAAMEN1KMT2A | |
| SCHEMBL19400401 | 0.74 | GAA (0.66) | ALDH1A1RECQLGAAMEN1KMT2A | |
| SCHEMBL5652363 | 0.72 | SMN1; SMN2 (0.76) | ALDH1A1RECQLGAAKMT2AKDM4E | |
| SCHEMBL2731374 | 0.71 | MPO (1.00) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL15613371 | 0.70 | ALDH1A1 (0.95) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL2731410 | 0.70 | MPO (1.00) | ALDH1A1MEN1KMT2ATSHRRXFP1 | |
| SCHEMBL23201147 | 0.69 | ALDH1A1 (0.61) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL30882314 | 0.69 | ALDH1A1 (0.61) | ALDH1A1GAAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9775835-B2 | Small molecule inhibitors of viral protein interactions with human t-RNA | SIRGA ADVANCED BIOPHARMA, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-20150190384-A1 | SMALL MOLECULE INHIBITORS OF VIRAL PROTEIN INTERACTIONS WITH HUMAN T-RNA | SIRGA ADVANCED BIOPHARMA, INC. (US) | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150190384-A1 | SMALL MOLECULE INHIBITORS OF VIRAL PROTEIN INTERACTIONS WITH HUMAN T-RNA | NSUN3, TARBP1, TRDMT1 | ALDH1A1 4753/4885RECQL 981/4885GAA 2044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.