Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 17/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 17/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19379653 | 0.90 | FAP (0.37) | PRMT5WDR77FAP | |
| SCHEMBL19401321 | 0.83 | FAP (0.38) | PRMT5WDR77FAP | |
| SCHEMBL19397140 | 0.82 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL19397138 | 0.81 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL15833093 | 0.80 | CYP3A4 (0.47) | — | |
| SCHEMBL17453235 | 0.80 | CYP3A4 (0.47) | — | |
| SCHEMBL31228172 | 0.80 | PRMT5 (0.45) | PRMT5WDR77 | |
| SCHEMBL19397136 | 0.79 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL21413061 | 0.78 | FAP (0.37) | PRMT5WDR77FAP | |
| SCHEMBL15833009 | 0.77 | HINT1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275329-A1 | ALKYNYL NUCLEOSIDE ANALOGS AS INHIBITORS OF HUMAN RHINOVIRUS | NOVARTIS INSTITUTE FOR TROPICAL DISEASES PTE LTD (SG) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275329-A1 | ALKYNYL NUCLEOSIDE ANALOGS AS INHIBITORS OF HUMAN RHINOVIRUS | RNASEH1, ENTPD5, SARNP | PRMT5 1834/4885WDR77 1571/4885FAP 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.