SCHEMBL1940302

SCHEMBL1940302

Cn1nc(C(=O)O)cc1-c1ccccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.64
MEN1 O00255 1/20 0.64
RPA1 P27694 2/20 0.47
PPP1CA P62136 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
MARS1 P56192 4/20 0.45
PLA2G10 O15496 1/20 0.45
POLB P06746 1/20 0.44
ALDH1A1 P00352 1/20 0.43
GRM5 P41594 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3436445 0.84 MARS1 (0.60) RPA1MARS1
SCHEMBL68817 0.83 PLA2G10 (0.49) KMT2AMEN1RPA1L3MBTL1PLA2G10
SCHEMBL1739614 0.81 MARS1 (0.60) KMT2AMEN1RPA1PPP1CAL3MBTL1
SCHEMBL4488941 0.81 KMT2A (0.82) KMT2AMEN1RPA1PPP1CAL3MBTL1
SCHEMBL15862514 0.79 MARS1 (0.47) KMT2AMEN1RPA1L3MBTL1MARS1
SCHEMBL570061 0.79 RPA1 (0.63) KMT2AMEN1RPA1PPP1CAL3MBTL1
SCHEMBL15671419 0.78 PLA2G10 (0.45) KMT2AMEN1RPA1L3MBTL1PLA2G10
SCHEMBL15869823 0.78 KMO (0.52) KMT2AMEN1RPA1PLA2G10ALDH1A1
SCHEMBL4486680 0.78 KMT2A (1.00) KMT2AMEN1RPA1PPP1CAL3MBTL1
SCHEMBL8486970 0.78 HSD11B1 (0.44) KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 EP disclosed