Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1942849 | 0.96 | CRHR1 (0.93) | CRHR1ERG | |
| SCHEMBL1942384 | 0.96 | CRHR1 (0.92) | CRHR1ERG | |
| SCHEMBL1942275 | 0.96 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL1942295 | 0.94 | CRHR1 (0.91) | CRHR1 | |
| SCHEMBL1942981 | 0.94 | CRHR1 (1.00) | CRHR1ERG | |
| SCHEMBL1942857 | 0.93 | CRHR1 (0.89) | CRHR1ERG | |
| SCHEMBL1944824 | 0.93 | CRHR1 (1.00) | CRHR1ERG | |
| SCHEMBL3469038 | 0.93 | CRHR1 (1.00) | CRHR1ERG | |
| SCHEMBL1942243 | 0.92 | CRHR1 (0.91) | CRHR1ERG | |
| SCHEMBL1942684 | 0.92 | CRHR1 (1.00) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389618-B1 | PYRAZOLO 1,5-A PYRIDINES AND MEDICINES CONTAINING THE SAME | EISAI R&D MAN CO LTD (JP) | 2011-06-15 | — | — | EP | disclosed |
| US-7625925-B2 | Pyrazolo[1,5-a]pyridines and medicines containing the same | EISAI R&D MANAGEMENT CO., LTD (JP) | 2009-12-01 | — | — | US | disclosed |
| US-20070249663-A1 | PYRAZOLO[1,5-a]PYRIDINES AND MEDICINES CONTAINING THE SAME | HIBI SHIGEKI | 2007-10-25 | — | — | US | disclosed |
| US-7285666-B2 | Pyrazolo[1,5-a] pyridines and medicines containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-20060217348-A1 | Pyrazolo[1,5-a] pyridines and medicines containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-09-28 | — | — | US | disclosed |
| US-7091215-B2 | Pyrazolo[1,5-a]pyridines and medicines containing the same | EISAI CO., LTD. (JP) | 2006-08-15 | — | — | US | disclosed |
| US-20040122039-A1 | Pyrazolo[1,5-a]pyridines and medicines containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249663-A1 | PYRAZOLO[1,5-a]PYRIDINES AND MEDICINES CONTAINING THE SAME | NR3C1, NR3C2, NR5A2 | CRHR1 186/4885ERG 2021/4885 |
| US-20040122039-A1 | Pyrazolo[1,5-a]pyridines and medicines containing the same | XDH, NR3C1, NR5A1 | CRHR1 195/4885ERG 2526/4885 |
| US-20060217348-A1 | Pyrazolo[1,5-a] pyridines and medicines containing the same | NR3C1, NR3C2, NR5A2 | CRHR1 186/4885ERG 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.