Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAF1 | P21675 | 8/20 | 0.61 |
| ▸ | BRD1 | O95696 | 8/20 | 0.61 |
| ▸ | BRPF1 | P55201 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404591 | 0.91 | BRD1 (0.71) | TAF1BRD1BRPF1KDM4EALDH1A1 | |
| SCHEMBL19404507 | 0.90 | TAF1 (0.58) | TAF1BRD1BRPF1KDM4EALDH1A1 | |
| SCHEMBL19404590 | 0.89 | TAF1 (0.57) | TAF1BRD1BRPF1KDM4EALDH1A1 | |
| SCHEMBL19404424 | 0.87 | MEN1 (0.54) | TAF1BRD1BRPF1KMT2ALMNA | |
| SCHEMBL19405012 | 0.84 | KDM4E (0.59) | TAF1BRD1BRPF1KDM4EALDH1A1 | |
| SCHEMBL19405016 | 0.82 | BRD1 (0.82) | TAF1BRD1BRPF1KDM4EALDH1A1 | |
| SCHEMBL19404427 | 0.81 | BRD1 (0.59) | TAF1BRD1BRPF1KMT2ALMNA | |
| SCHEMBL19404528 | 0.78 | BRD1 (0.71) | TAF1BRD1BRPF1LMNABRD4 | |
| SCHEMBL19405020 | 0.78 | BRD1 (0.61) | TAF1BRD1BRPF1KDM4EKMT2A | |
| SCHEMBL16213400 | 0.76 | KDM4E (1.00) | TAF1BRD1BRPF1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |