Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TAF1 | P21675 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | BRD1 | O95696 | 2/20 | 0.53 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19405004 | 0.87 | TAF1 (0.56) | KDM4EALDH1A1HPGDTAF1KMT2A | |
| SCHEMBL19404431 | 0.87 | USP2 (0.59) | KDM4EALDH1A1HPGDTAF1KMT2A | |
| SCHEMBL19404618 | 0.85 | MEN1 (0.60) | KDM4EALDH1A1HPGDTAF1KMT2A | |
| SCHEMBL19405013 | 0.84 | TAF1 (0.61) | KDM4EALDH1A1HPGDTAF1KMT2A | |
| SCHEMBL19404790 | 0.84 | ALDH1A1 (0.60) | KDM4EALDH1A1TAF1KMT2AMEN1 | |
| SCHEMBL19404589 | 0.83 | BRD1 (0.64) | KDM4EALDH1A1HPGDTAF1KMT2A | |
| SCHEMBL19404591 | 0.83 | BRD1 (0.71) | KDM4EALDH1A1HPGDTAF1KMT2A | |
| SCHEMBL19757543 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HPGDTAF1KMT2A | |
| SCHEMBL19405011 | 0.81 | BRD1 (0.69) | KDM4EALDH1A1HPGDTAF1KMT2A | |
| SCHEMBL19405025 | 0.81 | BRD1 (0.58) | KDM4EALDH1A1HPGDTAF1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |