Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5522534 | 0.98 | MEN1 (0.34) | MEN1POLBKMT2ATSHRCYP2C19 | |
| SCHEMBL5032422 | 0.87 | — | — | |
| Trifluoroacetic Acid SCHEMBL2496570 | 0.87 | CPB2 (0.34) | MEN1POLBKMT2A | |
| Trifluoroacetic Acid SCHEMBL2496292 | 0.84 | TACR1 (0.32) | — | |
| SCHEMBL7432173 | 0.84 | TSHR (0.33) | MEN1POLBKMT2ATSHRCYP2C19 | |
| SCHEMBL11794573 | 0.81 | TSHR (0.30) | TSHRCYP2C19 | |
| SCHEMBL21267725 | 0.79 | — | — | |
| SCHEMBL2055524 | 0.73 | HSD11B1 (0.44) | MEN1POLBKMT2ALMNAALDH1A1 | |
| SCHEMBL14721217 | 0.73 | MEN1 (0.38) | MEN1POLBKMT2ALMNA | |
| SCHEMBL14721219 | 0.73 | MEN1 (0.38) | MEN1POLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185155-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING DOPAMINE RECEPTOR LIGANDS AND METHODS OF TREATMENT USING DOPAMINE RECPTOR LIGANDS | RICHTER GEDEON NYRT (HU) | 2017-10-04 | — | — | EP | claimed |