Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11794573 | 0.98 | TSHR (0.30) | TSHRCYP2C19 | |
| SCHEMBL19406478 | 0.84 | MEN1 (0.37) | TSHRCYP2C19MEN1POLBKMT2A | |
| SCHEMBL5522534 | 0.81 | MEN1 (0.34) | TSHRCYP2C19MEN1POLBKMT2A | |
| SCHEMBL21267725 | 0.77 | — | — | |
| Trifluoroacetic Acid SCHEMBL2496570 | 0.72 | CPB2 (0.34) | MEN1POLBKMT2A | |
| SCHEMBL27274994 | 0.71 | LMNA (0.33) | LMNA | |
| SCHEMBL12402118 | 0.70 | TSHR (0.39) | TSHRCYP2C19LMNA | |
| SCHEMBL5032422 | 0.70 | — | — | |
| SCHEMBL6473327 | 0.70 | HSD11B1 (0.32) | — | |
| Trifluoroacetic Acid SCHEMBL2496292 | 0.70 | TACR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147078-A1 | ACETYLENIC (BETA)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | American Cyanamid Company (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000044711-A1 | ACETYLENIC $G(b)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |