Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PGK1 | P00558 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | CHUK | O15111 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 5/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19409225 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1YTHDC1KDM4EPGK1 | |
| SCHEMBL19409235 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1YTHDC1KDM4EPGK1 | |
| SCHEMBL19409234 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1YTHDC1IKBKBCHUK | |
| SCHEMBL19409262 | 0.78 | PGK1 (0.34) | SMN1; SMN2ALDH1A1KDM4EPGK1POLB | |
| SCHEMBL19409218 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EPGK1IKBKBCHUK | |
| SCHEMBL25658511 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KDM4EIKBKBCHUK | |
| SCHEMBL27967127 | 0.73 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1YTHDC1PDE4APDE4B | |
| SCHEMBL19409251 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KDM4ESYKPOLB | |
| SCHEMBL19827043 | 0.70 | — | — | |
| SCHEMBL19420515 | 0.69 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1YTHDC1KDM4EPGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | claimed |
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | disclosed |
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | disclosed |
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | KRT18, DHODH, AOC1 | SMN1; SMN2 4868/4885ALDH1A1 45/4885YTHDC1 3771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.