Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19409257 | 0.82 | ADORA2A (0.41) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL19409250 | 0.80 | SMN1; SMN2 (0.39) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL19409218 | 0.78 | SMN1; SMN2 (0.41) | ADORA2AADORA1CDK1KDM4ENLRP3 | |
| SCHEMBL19409262 | 0.77 | PGK1 (0.34) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL19409223 | 0.75 | ADORA2A (0.36) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL19409261 | 0.73 | ADORA2A (0.43) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL12835589 | 0.73 | — | — | |
| SCHEMBL19420515 | 0.72 | SMN1; SMN2 (0.36) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL6611707 | 0.69 | PKM (0.47) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL19409225 | 0.65 | SMN1; SMN2 (0.56) | CDK1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | claimed |
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | disclosed |
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | disclosed |
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | KRT18, DHODH, AOC1 | ADORA2A 4540/4885ADORA1 3310/4885PI4KA 2166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.