Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28529167 | 0.84 | PLA2G2A (0.67) | PLA2G2AKMT2AMEN1PKMTP53 | |
| SCHEMBL4727671 | 0.83 | PLA2G2A (0.54) | PLA2G2AKMT2AMEN1TP53TSHR | |
| SCHEMBL17911632 | 0.81 | KCNA3 (0.38) | PLA2G2A | |
| SCHEMBL10830829 | 0.81 | PLA2G2A (0.86) | PLA2G2AKMT2ATP53TSHRPLA2G4B | |
| SCHEMBL1925564 | 0.81 | PKM (0.67) | PKMTP53TSHRPLA2G4BALDH1A1 | |
| SCHEMBL1543649 | 0.80 | PLA2G2A (0.62) | PLA2G2AKMT2AMEN1PKMTP53 | |
| SCHEMBL23352169 | 0.79 | PLA2G2A (0.96) | PLA2G2AKMT2ATP53TSHRPLA2G4B | |
| SCHEMBL3487150 | 0.79 | PLA2G2A (0.67) | PLA2G2AKMT2AMEN1PKMTP53 | |
| SCHEMBL2188463 | 0.78 | PLA2G2A (0.61) | PLA2G2AKMT2AMEN1PKMTP53 | |
| SCHEMBL2958348 | 0.78 | PLA2G2A (0.61) | PLA2G2AKMT2AMEN1PKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9970947-B2 | Fluorescent probe | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2018-05-15 | — | — | US | disclosed |
| US-20170285045-A1 | FLUORESCENT PROBE | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170285045-A1 | FLUORESCENT PROBE | FLI1, TFEB, SLCO1B1 | PLA2G2A 4098/4885KMT2A 3992/4885MEN1 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.