Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21496937 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AGAAGFER | |
| SCHEMBL28686 | 0.84 | MAPT (0.54) | ALDH1A1GAAPOLBNOS1MAPT | |
| SCHEMBL29471420 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AGAAGFER | |
| SCHEMBL28549 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AGAAGFER | |
| SCHEMBL30597526 | 0.84 | MAPT (0.54) | ALDH1A1GAAPOLBNOS1MAPT | |
| Methane SCHEMBL27929615 | 0.82 | MAPT (0.53) | ALDH1A1GAAPOLBNOS1MAPT | |
| Ammonia Solution, Strong SCHEMBL28394313 | 0.82 | MAPT (0.53) | ALDH1A1GAAPOLBNOS1MAPT | |
| SCHEMBL8178724 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AGAAGFER | |
| Phosphoric Acid SCHEMBL594274 | 0.77 | MAPT (0.47) | GAAPOLBNOS1MAPTMAOB | |
| Pyridine SCHEMBL28517154 | 0.76 | MAPT (0.48) | POLBNOS1MAPTMAOBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10876121-B2 | EGFR nucleic acids and uses thereof | AVIDITY BIOSCIENCES, INC. (US) | 2020-12-29 | — | — | US | disclosed |
| US-10858656-B2 | KRAS nucleic acids and uses thereof | AVIDITY BIOSCIENCES, INC. (US) | 2020-12-08 | — | — | US | disclosed |
| US-20170362597-A1 | EGFR NUCLEIC ACIDS AND USES THEREOF | AVIDITY BIOSCIENCES, INC. | 2017-12-21 | — | — | US | disclosed |
| US-20170283476-A1 | MYC NUCLEIC ACIDS AND USES THEREOF | AVIDITY BIOSCIENCES, INC. | 2017-10-05 | — | — | US | disclosed |
| US-20170283806-A1 | KRAS NUCLEIC ACIDS AND USES THEREOF | AVIDITY BIOSCIENCES, INC. | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283476-A1 | MYC NUCLEIC ACIDS AND USES THEREOF | MYC, MYCBP, MYCBP2 | ALDH1A1 3433/4885MEN1 1070/4885KMT2A 1006/4885 |
| US-10876121-B2 | EGFR nucleic acids and uses thereof | EGFR, ERBB3, ERBB2 | ALDH1A1 3983/4885MEN1 4283/4885KMT2A 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.