SCHEMBL28549

SCHEMBL28549

O=[N+]([O-])c1cccc2[nH]ccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
TDP1 Q9NUW8 3/20 0.57
NOS1 P29475 2/20 0.54
AHR P35869 1/20 0.47
GPR35 Q9HC97 1/20 0.45
GAA P10253 4/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
MAPT P10636 4/20 0.45
POLB P06746 1/20 0.43
HRH4 Q9H3N8 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
TSHR P16473 2/20 0.41
GFER P55789 1/20 0.41
NPC1 O15118 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAPK1 P28482 2/20 0.41
PARP1 P09874 1/20 0.41
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29471420 1.00 ALDH1A1 (0.64) ALDH1A1TDP1NOS1AHRGPR35
SCHEMBL15596459 0.84 ALDH1A1 (0.51) ALDH1A1TDP1NOS1AHRGAA
SCHEMBL21496937 0.84 ALDH1A1 (0.48) ALDH1A1TDP1NOS1GAAMEN1
SCHEMBL19410285 0.84 ALDH1A1 (0.48) ALDH1A1TDP1NOS1GAAMEN1
Ethoxycarbonyl Group SCHEMBL27704233 0.83 ALDH1A1 (0.47) ALDH1A1TDP1NOS1AHRGAA
SCHEMBL2004209 0.82 NR4A2 (0.49) ALDH1A1TDP1MEN1KMT2AMAPT
SCHEMBL29708278 0.81 TDP1 (0.53) ALDH1A1TDP1NOS1GPR35GAA
SCHEMBL12320528 0.81 L3MBTL1 (0.53) ALDH1A1TDP1NOS1GAASMN1; SMN2
SCHEMBL30098446 0.78 ALDH1A1 (1.00) ALDH1A1TDP1NOS1GAAMEN1
SCHEMBL307488 0.78 ALDH1A1 (1.00) ALDH1A1TDP1NOS1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3030 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630851-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-19 US claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US claimed
US-20240229109-A1 METHODS FOR IDENTIFICATION AND RATIO DETERMINATION OF RNA SPECIES IN MULTIVALENT RNA COMPOSITIONS MODERNATX, INC. (US) 2024-07-11 US claimed
CN-115920902-B Method for preparing oxygen-enriched defect graphene encapsulated metal nickel catalyst by ultrasonic assistance and application of method 浙江工业大学 2024-06-11 CN claimed
CN-117567498-A Sodium hydride suspension and application thereof in flow chemical reaction 武汉药明康德新药开发有限公司 2024-02-20 CN claimed
EP-4314332-A2 METHODS FOR IDENTIFICATION AND RATIO DETERMINATION OF RNA SPECIES IN MULTIVALENT RNA COMPOSITIONS ModernaTX, Inc. (US) 2024-02-07 EP claimed
CN-117069063-A Sodium hydride suspension and application thereof in flow chemical reaction 武汉药明康德新药开发有限公司 2023-11-17 CN claimed
US-20230250474-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-10 US claimed
US-20230212645-A1 METHODS AND COMPOSITIONS FOR RNA MAPPING MODERNATX, INC. (US) 2023-07-06 US claimed
CN-114394963-B Isoxazoline compound, preparation method and application 西北农林科技大学 2023-05-23 CN claimed
WO-2006031745-A2 METHODS FOR LONG-RANGE SEQUENCE ANALYSIS OF NUCLEIC ACIDS SEQUENOM, INC. (US) 2006-03-23 WO claimed
WO-2006028503-A1 PEPTIDE-BASED BODY SURFACE REAGENTS FOR PERSONAL CARE E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-03-16 WO claimed
US-20050226839-A1 Pepetide-based body surface reagents for personal care E. I. DU PONT DE NEMOURS AND COMPANY 2005-10-13 US claimed
WO-2005025505-A2 PEPTIDE-BASED CONDITIONERS AND COLORANTS FOR HAIR, SKIN, AND NAILS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-03-24 WO claimed
US-20050050656-A1 Peptide-based conditioners and colorants for hair, skin, and nails E. I. DU PONT DE NEMOURS AND COMPANY 2005-03-10 US claimed
US-20040014101-A1 Separating and/or identifying polymorphic nucleic acids using universal bases PEL-FREEZ CLINICAL SYSTEMS, INC. 2004-01-22 US claimed
US-6635427-B2 Kit for use in the amplification and quantification of preferential sequences UNIVERSITY OF UTAH RESEARCH FOUNDATION 2003-10-21 US claimed
EP-1307592-A2 SINGLE-LABELED OLIGONUCLEOTIDE PROBES University of Utah Research Foundation (US) 2003-05-07 EP claimed
US-20030022177-A1 Single-labeled oligonucleotide probes for homogeneous nucleic acid sequence analysis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-01-30 US claimed
WO-2002014555-A2 SINGLE-LABELED OLIGONUCLEOTIDE PROBES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2002-02-21 WO claimed