Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410285 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AGAAGFER | |
| SCHEMBL29471420 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AGAAGFER | |
| SCHEMBL29904251 | 0.84 | MAPT (0.54) | ALDH1A1MAPTNOS1CYP3A4LMNA | |
| SCHEMBL28549 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AGAAGFER | |
| SCHEMBL30011 | 0.84 | MAPT (0.54) | ALDH1A1MAPTNOS1CYP3A4LMNA | |
| Indole SCHEMBL710464 | 0.83 | TRPA1 (0.55) | ALDH1A1MEN1KMT2APKMPKLR | |
| Pyrimidine SCHEMBL28222787 | 0.77 | MAPT (0.49) | ALDH1A1MEN1KMT2AMAPTNOS1 | |
| SCHEMBL8487610 | 0.75 | TDP1 (0.50) | ALDH1A1MEN1KMT2APKMPKLR | |
| SCHEMBL1225953 | 0.74 | PGR (0.51) | MEN1KMT2AMAPTLMNAPOLB | |
| Indole SCHEMBL27976837 | 0.73 | TRPA1 (0.63) | ALDH1A1MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781711-A1 | SINGLE-STRANDED BREAK DETECTION IN DOUBLE-STRANDED DNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2019204585-A1 | SINGLE-STRANDED BREAK DETECTION IN DOUBLE-STRANDED DNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-10-24 | — | — | WO | disclosed |