SCHEMBL19411348

SCHEMBL19411348

C#Cc1cccc2c1C(=O)N(c1ccc(OC(C)=O)cc1)C2=O.c1cc2ccc1-2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.48
MEN1 O00255 4/20 0.48
NPC1 O15118 2/20 0.48
TLR9 Q9NR96 2/20 0.48
GLA P06280 1/20 0.44
AHR P35869 1/20 0.42
HSD17B10 Q99714 4/20 0.41
HPGD P15428 3/20 0.40
KDM4E B2RXH2 1/20 0.40
ADORA2A P29274 1/20 0.40
LMNA P02545 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
GAA P10253 1/20 0.39
ALDH1A1 P00352 2/20 0.39
HTT P42858 2/20 0.39
CACNA1B Q00975 2/20 0.39
APBA1 Q02410 2/20 0.39
ATM Q13315 2/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19411342 0.81 CA12 (0.57) KMT2AMEN1HPGDKDM4EL3MBTL1
SCHEMBL7686000 0.80 HSPA1A (0.56) KMT2AMEN1HSD17B10KDM4EADORA2A
SCHEMBL7150732 0.77 GLA (0.61) KMT2AMEN1NPC1TLR9GLA
SCHEMBL28505833 0.75 NPC1 (0.54) KMT2AMEN1NPC1TLR9KDM4E
SCHEMBL28484463 0.74 TYMS (0.62) KMT2AMEN1HSD17B10HPGDKDM4E
SCHEMBL10796884 0.74 KMT2A (0.63) KMT2AMEN1NPC1TLR9GLA
SCHEMBL10747857 0.74 ADORA2A (0.37) KMT2AMEN1AHRADORA2A
SCHEMBL3447118 0.73 HSPA1A (0.41) NPC1KDM4EADORA2AALDH1A1RAB9A
SCHEMBL6910591 0.72 MEN1 (0.49) KMT2AMEN1ADORA2AALDH1A1MAPT
SCHEMBL11537116 0.69 HSD17B10 (0.61) KMT2AMEN1NPC1TLR9GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717360-A High-heat-resistance LCP material easy to mold and process and preparation method thereof 宁夏清研高分子新材料有限公司 2021-11-30 CN claimed
CN-113717360-A High-heat-resistance LCP material easy to mold and process and preparation method thereof 宁夏清研高分子新材料有限公司 2021-11-30 CN disclosed
CN-113717360-A High-heat-resistance LCP material easy to mold and process and preparation method thereof 宁夏清研高分子新材料有限公司 2021-11-30 CN disclosed
CN-109563244-B Fully aromatic high performance block copolymers 同素异形体科技有限公司 2021-06-25 CN disclosed
US-10954442-B2 All-aromatic high-performance block-copolymers Allotropica Technologies, Inc. (US) 2021-03-23 US disclosed
US-20190119574-A1 ALL-AROMATIC HIGH-PERFORMANCE BLOCK-COPOLYMERS Allotropica Technologies, Inc. (US) 2019-04-25 US disclosed
EP-3436499-A1 ALL-AROMATIC HIGH-PERFORMANCE BLOCK-COPOLYMERS Allotropica Technologies Inc. (US) 2019-02-06 EP disclosed
WO-2017171547-A1 ALL-AROMATIC HIGH-PERFORMANCE BLOCK-COPOLYMERS TECHNISCHE UNIVERSITEIT DELFT (NL) 2017-10-05 WO disclosed