SCHEMBL19411968

SCHEMBL19411968

c1ccc(NOc2ccc(ONc3ccccc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
TDP1 Q9NUW8 3/20 0.43
HSD17B10 Q99714 2/20 0.43
CTSD P07339 1/20 0.43
TSHR P16473 4/20 0.41
PTGS2 P35354 2/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
MAPK1 P28482 1/20 0.41
HTR2B P41595 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP1A2 P05177 3/20 0.39
CYP2C19 P33261 3/20 0.39
IDO1 P14902 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
LMNA P02545 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251644 0.94 ALDH1A1 (0.43) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL29448429 0.93 CYP1A2 (0.38) ALDH1A1TDP1HSD17B10CTSDTSHR
SCHEMBL29288587 0.93 LTA4H (0.50) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL10773638 0.91 ALDH1A1 (0.59) ALDH1A1TDP1HSD17B10TSHRPTGS2
SCHEMBL8760585 0.91 CYP1A2 (0.41) ALDH1A1TDP1HSD17B10CTSDMAPK1
SCHEMBL1283610 0.89 HPGD (0.47) ALDH1A1MEN1KMT2ALTA4HAR
SCHEMBL29006124 0.89 MAPT (0.52) ALDH1A1TDP1HSD17B10TSHRPTGS2
SCHEMBL1283693 0.89 ALDH1A1 (0.44) ALDH1A1TDP1MAPK1L3MBTL1LMNA
SCHEMBL623079 0.89 HPGD (0.50) ALDH1A1TDP1HSD17B10TSHRPTGS2
SCHEMBL8590182 0.89 CA4 (0.54) ALDH1A1TDP1HSD17B10ALOX12MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113968878-A Hyperbranched boric acid modified phthalonitrile monomer and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-01-25 CN claimed
CN-113388109-B Polyimide with main chain containing benzonorbornene structure and preparation method thereof 南昌大学 2023-01-31 CN disclosed
CN-114853696-A Bio-based intrinsic flame-retardant epoxy monomer and preparation method and application thereof 厦门大学 2022-08-05 CN disclosed
CN-108884023-B Bisphenol M bisphthalonitrile ether resin, bisphenol P bisphthalonitrile ether resin, preparation methods thereof, resin blend and two-component system 3M创新有限公司 2022-02-25 CN disclosed
CN-113968878-A Hyperbranched boric acid modified phthalonitrile monomer and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-01-25 CN disclosed
EP-3436502-A1 RESIN BLENDS OF RESORCINOL DIPHTHALONITRILE ETHER WITH BISPHENOL M DIPHTHALONITRILE ETHER AND/OR BISPHENOL T DIPHTHALONITRILE ETHER 3M Innovative Properties Company (US) 2019-02-06 EP disclosed
WO-2017173040-A1 RESIN BLENDS OF RESORCINOL DIPHTHALONITRILE ETHER WITH BISPHENOL M DIPHTHALONITRILE ETHER AND/OR BISPHENOL T DIPHTHALONITRILE ETHER 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-10-05 WO disclosed