Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448429 | 0.98 | CYP1A2 (0.38) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL8896647 | 0.91 | ALDH1A1 (0.41) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL19411968 | 0.91 | ALDH1A1 (0.43) | CYP1A2GAACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL29354416 | 0.88 | CYP1A2 (0.52) | CYP1A2GAAALDH1A1TDP1MEN1 | |
| SCHEMBL29353450 | 0.88 | CYP1A2 (0.49) | CYP1A2GAACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL251644 | 0.85 | ALDH1A1 (0.43) | CYP1A2CYP2C9CYP2C19ALDH1A1HSD17B10 | |
| SCHEMBL29288587 | 0.84 | LTA4H (0.50) | ALDH1A1CA1CA2CA9MEN1 | |
| SCHEMBL29351769 | 0.83 | NPSR1 (0.43) | GAACYP2C19ALDH1A1TDP1MAPK1 | |
| SCHEMBL10773638 | 0.82 | ALDH1A1 (0.59) | CYP1A2GAACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL1283693 | 0.80 | ALDH1A1 (0.44) | GAAALDH1A1TDP1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994001-A | NOTCH signaling pathway inhibitors and their use in cancer treatment | 塞莱斯蒂亚生物技术股份公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-113966324-B | NOTCH signaling pathway inhibitors and their use in cancer treatment | 塞莱斯蒂亚生物技术股份公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-113966324-A | NOTCH signaling pathway inhibitors and their use in cancer treatment | 塞莱斯蒂亚生物技术股份公司 | 2022-01-21 | — | — | CN | disclosed |
| EP-0562824-B1 | Thermal recording material | FUJI PHOTO FILM CO LTD (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5464804-A | Heat sensitive color layer with electron donor, colorless dye is black color aminofluoran, amino compound and isocyanate compound | FUJI PHOTO FILM CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| US-5288688-A | Comprising electron-donating colorless dye, isocyanate and amino compounds; antifogging, discoloration inhibition, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0562824-A2 | Thermal recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |