(-)-Epicatechin

(-)-Epicatechin

SCHEMBL19412

Oc1cc(O)c2c(c1)O[C@H](c1ccc(O)c(O)c1)[C@H](O)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 6/20 1.00
KDM4E B2RXH2 6/20 1.00
HSD17B10 Q99714 5/20 1.00
SNCA P37840 5/20 1.00
ALDH1A1 P00352 4/20 1.00
MAPT P10636 4/20 1.00
PTGS1 P23219 4/20 1.00
ALOX15 P16050 4/20 1.00
GAA P10253 3/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
APEX1 P27695 3/20 1.00
RECQL P46063 3/20 1.00
CYP3A4 P08684 3/20 1.00
PKM P14618 2/20 1.00
ALPL P05186 2/20 1.00
POLB P06746 2/20 1.00
PTGS2 P35354 2/20 1.00
RAD52 P43351 2/20 1.00
HPGD P15428 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Catechin SCHEMBL10001669 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
(+)-Epicatechin SCHEMBL862089 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL1330653 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Catechin SCHEMBL10033927 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL12392372 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL13610161 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Catechin SCHEMBL19411 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL19741 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL5081456 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
(-)-Catechin SCHEMBL166733 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 24363 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107510-A1 HOT-MELT ADHESIVE COMPOSITION AND METHOD OF APPLICATION BIOBOND ADHESIVES, INC. (US) 2026-05-21 WO claimed
EP-4743071-A2 DIPHENYLETHYLENE COMPOUNDS AND COMPOSITIONS THEREOF INNOVENE INC. (US) 2026-05-20 EP claimed
EP-4514146-B1 A COMBINATION FOR USE IN THE PREPARATION OF A DRINKABLE FOAMING OR FOAMABLE LIQUID, A DEVICE AND A METHOD FOR PREPARING AND DISPENSING A DRINKABLE FOAMING OR FOAMABLE LIQUID BAR ON B V (BE) 2026-05-13 EP claimed
US-20260020595-A1 MOIST ORAL COMPOSITIONS NICOVENTURES TRADING LTD (GB) 2026-01-22 US claimed
US-12439952-B2 Moist oral compositions Nicoventures Trading Limited (GB) 2025-10-14 US claimed
EP-4447957-B1 COMPOSITIONS FOR THE TREATMENT OF FGFR3-RELATED COGNITIVE DEFICITS WITH A CATECHIN INST NAT SANTE RECH MED (FR) 2025-09-17 EP claimed
EP-4547242-A1 COMPOSITION FOR THE TREATMENT OF THE HUMAN PAPILLOMAVIRUS INFECTION (HPV) LO.LI. Pharma S.r.l. (IT) 2025-05-07 EP claimed
CN-119632976-A Use of (-) -epicatechin for inhibiting MEZ-induced toxicity 中国农业科学院农产品加工研究所 2025-03-18 CN claimed
EP-4514146-A1 A COMBINATION FOR USE IN THE PREPARATION OF A DRINKABLE FOAMING OR FOAMABLE LIQUID, A DEVICE AND A METHOD FOR PREPARING AND DISPENSING A DRINKABLE FOAMING OR FOAMABLE LIQUID Bar.on B.V. (BE) 2025-03-05 EP claimed
US-20250064996-A1 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF RAYZEBIO, INC. 2025-02-27 US claimed
US-4906656-A Biocidal treatment of materials with catechins BOARD OF CONTROL OF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 1990-03-06 US claimed
US-4906480-A Sweetness and flavor enhanced compositions and method of preparing such compositions FORSYTH DENTAL INFIRMARY FOR CHILDREN (US) 1990-03-06 US claimed
US-4760088-A Biocidal derivatives of catechins BOARD OF CONTROL OF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 1988-07-26 US claimed
US-4680193-A Solubilization of tea in cold water with catechin NESTEC S.A. (CH) 1987-07-14 US claimed
EP-0201000-A2 Stabilisation of tea in cold water SOCIETE DES PRODUITS NESTLE S.A. (CH) 1986-11-12 EP claimed
US-4613672-A SOLVENT EXTRACTION MITSU NORIN CO., LTD. (JP) 1986-09-23 US claimed
US-4585738-A FOOD PROCESSING KRAFT, INC. (US) 1986-04-29 US claimed
US-4517175-A FLAVANOL DERIVATIVES AND PROTEINS KAO CORPORATION (JP) 1985-05-14 US claimed
US-4248789-A MIXING CAFFEINE SOLUTION WITH TANNIC SOLUTION EXTRACTED FROM TEA DIRECTOR OF NATIONAL RESEARCH INSTITUTE OF TEA (JP) 1981-02-03 US claimed
US-4166861-A ESTERS OF CATECHIN AND EPICATECHIN; ANTILIPEMIC, ANTICHOLESTEROL, HEPATOPROTECTIVE INVERNI DELLA BEFFA S.P.A. (IT) 1979-09-04 US claimed