(-)-Catechin

(-)-Catechin

SCHEMBL166733

Oc1cc(O)c2c(c1)O[C@@H](c1ccc(O)c(O)c1)[C@H](O)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 6/20 1.00
KDM4E B2RXH2 6/20 1.00
HSD17B10 Q99714 5/20 1.00
SNCA P37840 5/20 1.00
ALDH1A1 P00352 4/20 1.00
MAPT P10636 4/20 1.00
PTGS1 P23219 4/20 1.00
ALOX15 P16050 4/20 1.00
GAA P10253 3/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
APEX1 P27695 3/20 1.00
RECQL P46063 3/20 1.00
CYP3A4 P08684 3/20 1.00
PKM P14618 2/20 1.00
ALPL P05186 2/20 1.00
POLB P06746 2/20 1.00
PTGS2 P35354 2/20 1.00
RAD52 P43351 2/20 1.00
HPGD P15428 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Catechin SCHEMBL10001669 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
(+)-Epicatechin SCHEMBL862089 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL1330653 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Catechin SCHEMBL10033927 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
(-)-Epicatechin SCHEMBL19412 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL12392372 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL13610161 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Catechin SCHEMBL19411 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL19741 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL5081456 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743071-A2 DIPHENYLETHYLENE COMPOUNDS AND COMPOSITIONS THEREOF INNOVENE INC. (US) 2026-05-20 EP claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
EP-4739297-A1 MODULATORS OF LYPOXYGENASES FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION SORBONNE UNIVERSITE (FR) 2026-05-13 EP claimed
EP-4426105-B1 COCOA PLANT CELL CULTURE PROCESSING METHODS AND PRODUCTS OBTAINED BY THE SAME ZHAW ZUERCHER HOCHSCHULE FUER ANGEWANDTE WSS (CH) 2026-04-29 EP claimed
US-20260103663-A1 ANTIMICROBIAL MATERIALS AND NANOPARTICLES AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2026-04-16 US claimed
EP-4714440-A2 A HEALING HERBAL-MINERAL COMPOSITION WITH ENHANCED EFFECTS Kurek, Janusz (PL) 2026-03-25 EP claimed
EP-4698522-A1 METHODS FOR PREPARING (-)-EPICATECHIN Mars, Incorporated (US) 2026-02-25 EP claimed
US-20260042741-A1 METHODS FOR PREPARING (-)-EPICATECHIN MARS, INCORPORATED (US) 2026-02-12 US claimed
US-12533386-B2 Preparation of black tea extract with high theaflavin content and use thereof Jiangsu Dehe BBiological Technology Co., Ltd. (CN) 2026-01-27 US claimed
EP-4678019-A1 AN AEROSOL GENERATING MATERIAL Nicoventures Trading Limited (GB) 2026-01-14 EP claimed
JP-2004506656-A 2004-03-04 JP claimed
WO-2003051287-A2 TOPICAL COMPOSITIONS AND METHODS FOR TREATMENT OF ADVERSE EFFECTS OF IONIZING RADIATION THE QUIGLEY CORPORATION (US) 2003-06-26 WO claimed
WO-2003043628-A1 MEDICAMENT FOR THE TREATMENT OF VIRAL SKIN AND TUMOUR DISEASES MEDIGENE AKTIENGESELLSCHAFT (DE) 2003-05-30 WO claimed
EP-1309333-A2 PLANT-DERIVED AND SYNTHETIC PHENOLIC COMPOUNDS AND PLANT EXTRACTS, EFFECTIVE IN THE TREATMENT AND PREVENTION OF CHLAMYDIAL INFECTIONS Control-Ox OY (FI) 2003-05-14 EP claimed
WO-2002014464-A2 PLANT-DERIVED AND SYNTHETIC PHENOLIC COMPOUNDS AND PLANT EXTRACTS, EFFECTIVE IN THE TREATMENT AND PREVENTION OF CHLAMYDIAL INFECTIONS CONTROL-OX OY (FI) 2002-02-21 WO claimed
EP-1089707-A1 USE OF COSMETIC COMPOSITIONS CONTAINING CATECHINS OR GREEN TEA EXTRACT FOR SUN-TANNING Beiersdorf Aktiengesellschaft (DE) 2001-04-11 EP claimed
WO-1999066897-A1 USE OF COSMETIC COMPOSITIONS CONTAINING CATECHINS OR GREEN TEA EXTRACT FOR SUN-TANNING BEIERSDORF AG (DE) 1999-12-29 WO claimed
EP-0789568-A4 ANTINEOPLASTIC COCOA EXTRACTS, METHODS FOR MAKING, USING MARS INC (US) 1998-10-21 EP claimed
EP-0789568-A1 ANTINEOPLASTIC COCOA EXTRACTS, METHODS FOR MAKING, USING Mars Incorporated (US) 1997-08-20 EP claimed
WO-1996010404-A1 ANTINEOPLASTIC COCOA EXTRACTS, METHODS FOR MAKING, USING MARS, INCORPORATED (US) 1996-04-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103663-A1 ANTIMICROBIAL MATERIALS AND NANOPARTICLES AND METHODS OF USE THEREOF DSTN, RHOA, FLOT1 BACE1 1024/4885KDM4E 2051/4885HSD17B10 4198/4885
US-20260042741-A1 METHODS FOR PREPARING (-)-EPICATECHIN CYP2E1, CYP1A1, ADH1A BACE1 3406/4885KDM4E 418/4885HSD17B10 361/4885
US-20260130395-A1 Water Dispersible Botanical Compositions TTPA, PNLIP, SRMS BACE1 3685/4885KDM4E 4113/4885HSD17B10 2881/4885
US-12533386-B2 Preparation of black tea extract with high theaflavin content and use thereof CAT, LPO, LIPC BACE1 1836/4885KDM4E 1008/4885HSD17B10 493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.