(+)-Epicatechin

(+)-Epicatechin

SCHEMBL862089

Oc1cc(O)c2c(c1)O[C@@H](c1ccc(O)c(O)c1)[C@@H](O)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 6/20 1.00
KDM4E B2RXH2 6/20 1.00
HSD17B10 Q99714 5/20 1.00
SNCA P37840 5/20 1.00
ALDH1A1 P00352 4/20 1.00
MAPT P10636 4/20 1.00
PTGS1 P23219 4/20 1.00
ALOX15 P16050 4/20 1.00
GAA P10253 3/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
APEX1 P27695 3/20 1.00
RECQL P46063 3/20 1.00
CYP3A4 P08684 3/20 1.00
PKM P14618 2/20 1.00
ALPL P05186 2/20 1.00
POLB P06746 2/20 1.00
PTGS2 P35354 2/20 1.00
RAD52 P43351 2/20 1.00
HPGD P15428 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Catechin SCHEMBL10001669 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL1330653 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Catechin SCHEMBL10033927 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
(-)-Epicatechin SCHEMBL19412 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL12392372 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL13610161 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Catechin SCHEMBL19411 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL19741 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
Cianidanol SCHEMBL5081456 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1
(-)-Catechin SCHEMBL166733 1.00 BACE1 (1.00) BACE1KDM4EHSD17B10SNCAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070924-A Refined snow chrysanthemum component and preparation method and application thereof 长春中医药大学 2026-05-22 CN claimed
WO-2025059302-A1 COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT AND MODULATION OF ACUTE AND CHRONIC SYMPTOMS OF MITOCHONDRIAL DISEASE AND DYSFUNCTION THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2025-03-20 WO claimed
US-20250064996-A1 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF RAYZEBIO, INC. 2025-02-27 US claimed
US-20250017895-A1 FLAVANOID CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF FOR THE TREATMENT OF MITOCHONDRIAL DISORDERS THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2025-01-16 US claimed
CN-118557475-A Camellia extract with soothing effect and preparation method and application thereof 青蛙王子(福建)婴童护理用品有限公司 2024-08-30 CN claimed
EP-4401724-A2 GREEN TEA-BASED NANOCOMPLEXES FOR EYE DISEASE Agency for Science, Technology and Research (SG) 2024-07-24 EP claimed
EP-4380633-A2 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF Rayzebio, Inc. (US) 2024-06-12 EP claimed
CN-118103078-A Stabilized compositions of radionuclides and uses thereof 瑞择生物公司 2024-05-28 CN claimed
CN-117451697-A Method for identifying Chinese gall or myrobalan vegetable dye and dyed fabric thereof 上海中纺联和生态科技有限公司 2024-01-26 CN claimed
WO-2023191839-A9 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF RAYZEBIO, INC. (US) 2023-11-09 WO claimed
CN-113740458-B Method for identifying picking seasons of tea leaves of shoume white tea 福建省农业科学院茶叶研究所 2023-05-26 CN claimed
WO-2023043367-A2 GREEN TEA-BASED NANOCOMPLEXES FOR EYE DISEASE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-03-23 WO claimed
CN-106659708-B Colloidal ball nanocomposite 新加坡科技研究局 2022-05-10 CN claimed
CN-114272335-A Traditional Chinese medicine formula for regulating and controlling intestinal function of children 华子昂 2022-04-05 CN claimed
EP-2668176-B1 A NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS SPHAERA PHARMA PTE LTD (SG) 2017-05-17 EP claimed
US-20170027902-A1 Use of a Composition Comprising a Flavonol, A Flavonoid, and a Fatty Acid in the Treatment of Oxidative Injuries Due to Mitochondrial Dysfunction ROBERTSON, GEORGE (CA) 2017-02-02 US claimed
US-9428482-B2 Process for synthesis of polyphenols SPHAERA PHARMA PTE. LTD. (SG) 2016-08-30 US claimed
WO-2015154192-A1 USE OF A COMPOSITION COMPRISING A FLAVONOL, A FLAVONOID, AND A FATTY ACID IN THE TREATMENT OF OXIDATIVE INJURIES DUE TO MITOCHONDRIAL DYSFUNCTION ROBERTSON GEORGE (CA) 2015-10-15 WO claimed
US-20140031421-A1 NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS SPHAERA PHARMA PTE. LTD. (SG) 2014-01-30 US claimed
US-20070160688-A1 Use of flavonoids to increase blood serum levels of dehydroepiandrosterone PROPRIETARY WELLNESS, LLC 2007-07-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070160688-A1 Use of flavonoids to increase blood serum levels of dehydroepiandrosterone SHBG, CYP17A1, HSD17B11 BACE1 3656/4885KDM4E 4677/4885HSD17B10 76/4885
US-20140031421-A1 NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS COMT, NQO1, SPR BACE1 3017/4885KDM4E 1066/4885HSD17B10 400/4885
US-20250064996-A1 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF TFRC, SLC39A14, EGFR BACE1 1741/4885KDM4E 3658/4885HSD17B10 4850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.