Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | SNCA | P37840 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 4/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | APEX1 | P27695 | 3/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | ALPL | P05186 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 2/20 | 1.00 |
| ▸ | RAD52 | P43351 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Catechin SCHEMBL10001669 | 1.00 | BACE1 (1.00) | BACE1KDM4EHSD17B10SNCAALDH1A1 | |
| (+)-Epicatechin SCHEMBL862089 | 1.00 | BACE1 (1.00) | BACE1KDM4EHSD17B10SNCAALDH1A1 | |
| Cianidanol SCHEMBL1330653 | 1.00 | BACE1 (1.00) | BACE1KDM4EHSD17B10SNCAALDH1A1 | |
| Catechin SCHEMBL10033927 | 1.00 | BACE1 (1.00) | BACE1KDM4EHSD17B10SNCAALDH1A1 | |
| (-)-Epicatechin SCHEMBL19412 | 1.00 | BACE1 (1.00) | BACE1KDM4EHSD17B10SNCAALDH1A1 | |
| Cianidanol SCHEMBL12392372 | 1.00 | BACE1 (1.00) | BACE1KDM4EHSD17B10SNCAALDH1A1 | |
| Cianidanol SCHEMBL13610161 | 1.00 | BACE1 (1.00) | BACE1KDM4EHSD17B10SNCAALDH1A1 | |
| Catechin SCHEMBL19411 | 1.00 | BACE1 (1.00) | BACE1KDM4EHSD17B10SNCAALDH1A1 | |
| Cianidanol SCHEMBL19741 | 1.00 | BACE1 (1.00) | BACE1KDM4EHSD17B10SNCAALDH1A1 | |
| (-)-Catechin SCHEMBL166733 | 1.00 | BACE1 (1.00) | BACE1KDM4EHSD17B10SNCAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293482-A1 | CENTRAL NERVOUS SYSTEM POTENTIATING COMPOSITION | SHIBAURA INSTITUTE OF TECHNOLOGY (JP) | 2023-09-21 | — | — | US | disclosed |
| WO-2020054996-A1 | FOAMABLE MOUTHWASH SOLID FORMULATION AND PREPARATION METHOD THEREFOR | (주)주환바이오.셀 | 2020-03-19 | — | — | WO | disclosed |
| US-9040250-B2 | Binding interaction of proanthocyanidins with bacteria and bacterial components | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2015-05-26 | — | — | US | disclosed |
| US-8715949-B2 | Applications of the binding interaction of proanthocyanidins with bacteria and bacterial components | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-05-06 | — | — | US | disclosed |
| US-8501970-B2 | Method for the preparation of C-4 coupled flavonoids, proanthocyanidins and analogues thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2013-08-06 | — | — | US | disclosed |
| US-8501970-B2 | Method for the preparation of C-4 coupled flavonoids, proanthocyanidins and analogues thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2013-08-06 | — | — | US | disclosed |
| WO-2011130705-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | CHROMOCELL CORPORATION (US) | 2011-10-20 | — | — | WO | disclosed |
| US-20110160467-A1 | Method for the Preparation of C-4 Coupled Flavonoids, Proanthocyanidins and Analogues Thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2011-06-30 | — | — | US | disclosed |
| US-20110160467-A1 | Method for the Preparation of C-4 Coupled Flavonoids, Proanthocyanidins and Analogues Thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2011-06-30 | — | — | US | disclosed |
| EP-2292226-A2 | The use of a polyphenol for the treatment of a cancerous or pre-cancerous lesion of the skin | MediGene AG (DE) | 2011-03-09 | — | — | EP | disclosed |
| WO-2009147645-A1 | METHOD FOR THE PREPARATION OF C-4 COUPLED FLAVONOIDS, PROANTHOCYANIDINS AND ANALOGUES THEREOF | UNIVERSITY OF THE FREE STATE (ZA) | 2009-12-10 | — | — | WO | disclosed |
| US-20080176933-A1 | BINDING INTERACTION OF PROANTHOCYANIDINS WITH BACTERIA AND BACTERIAL COMPONENTS | THE GOVERNMENT OF THE US, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-07-24 | — | — | US | disclosed |
| EP-1355708-B1 | PROCESS FOR EXTRACTING COMPOUNDS FROM PLANTS | UNIV MINNESOTA (US) | 2008-04-30 | — | — | EP | disclosed |
| US-20080064050-A1 | APPLICATIONS OF THE BINDING INTERACTION OF PROANTHOCYANIDINS WITH BACTERIA AND BACTERIAL COMPONENTS | THE GOVERNMENT OF THE US, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-03-13 | — | — | US | disclosed |
| US-7169763-B2 | Cytochrome P450 3A inhibitors and enhancers | Hu, Oliver Yoa-Pu (TW) | 2007-01-30 | — | — | US | disclosed |
| US-20030166584-A1 | Cytochrome P450 3A inhibitors and enhancers | NATIONAL SCIENCE COUNCIL (TW) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160467-A1 | Method for the Preparation of C-4 Coupled Flavonoids, Proanthocyanidins and Analogues Thereof | C9, PROC, MLN | BACE1 4671/4885KDM4E 543/4885HSD17B10 2586/4885 |
| US-20230293482-A1 | CENTRAL NERVOUS SYSTEM POTENTIATING COMPOSITION | CHRNA7, CHRNB3, CHRNA3 | BACE1 1564/4885KDM4E 4394/4885HSD17B10 1946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.