Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19412680 | 0.89 | POLRMT (0.35) | POLRMTDOT1L | |
| SCHEMBL19412770 | 0.83 | — | — | |
| SCHEMBL17106714 | 0.76 | POLRMT (0.35) | POLRMTDOT1L | |
| SCHEMBL19101755 | 0.76 | POLRMT (0.38) | POLRMT | |
| SCHEMBL17130417 | 0.75 | POLRMT (0.37) | POLRMTDOT1L | |
| SCHEMBL17106845 | 0.75 | POLRMT (0.37) | POLRMTDOT1L | |
| Phosphoric Acid SCHEMBL17106863 | 0.72 | POLRMT (0.40) | POLRMTDOT1L | |
| SCHEMBL19412426 | 0.72 | POLRMT (0.34) | POLRMTDOT1L | |
| SCHEMBL23054687 | 0.71 | POLRMT (0.46) | POLRMTDOT1L | |
| SCHEMBL29323823 | 0.71 | POLRMT (0.46) | POLRMTDOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777035-B2 | 4′-substituted nucleoside reverse transcriptase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-10-03 | — | — | US | disclosed |