Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13171570 | 0.79 | KDM4E (0.52) | NOS3NOS1NOS2KDM4EHPGD | |
| SCHEMBL23353702 | 0.79 | NOS3 (0.39) | NOS3NOS1NOS2KDM4EHPGD | |
| SCHEMBL18956890 | 0.79 | NOS2 (0.47) | NOS3NOS1NOS2KDM4EHPGD | |
| SCHEMBL10730430 | 0.75 | NOS3 (0.46) | NOS3NOS1NOS2KDM4EELANE | |
| SCHEMBL1161623 | 0.73 | CCR1 (0.50) | NOS3NOS1NOS2ELANE | |
| SCHEMBL5517171 | 0.73 | NOS3 (0.44) | NOS3NOS1NOS2KDM4EHPGD | |
| SCHEMBL1161423 | 0.73 | CCR1 (0.50) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL2125060 | 0.73 | NOS3 (0.50) | NOS3NOS1NOS2 | |
| SCHEMBL27997635 | 0.73 | NOS3 (0.44) | NOS3NOS1NOS2 | |
| SCHEMBL27778961 | 0.73 | NOS3 (0.44) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9780310-B2 | Heterocyclic compound for organic electroluminescent device and its application | TOSOH CORPORATION (JP) | 2017-10-03 | — | — | US | disclosed |