Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23192881 | 0.82 | DHFR (0.44) | DHFRCASRSLC6A4SLC6A2ACP3 | |
| SCHEMBL21976685 | 0.82 | AOC3 (0.39) | SLC6A4AOC3CYP2C19APLNRALDH1A1 | |
| SCHEMBL15951861 | 0.80 | OPRM1 (0.36) | DHFRADRB2SLC6A4AOC3OPRK1 | |
| SCHEMBL9063602 | 0.78 | AOC3 (0.43) | CYP2B6DHFRSLC6A4SLC6A2ACP3 | |
| SCHEMBL19415421 | 0.76 | SLC6A2 (0.39) | CYP2B6ADRB2ADRB1ADRB3SLC6A4 | |
| SCHEMBL8310048 | 0.76 | MEN1 (0.41) | CYP2B6ADRB2ADRB1ADRB3SLC6A4 | |
| SCHEMBL8310050 | 0.76 | MEN1 (0.41) | CYP2B6ADRB2ADRB1ADRB3SLC6A4 | |
| SCHEMBL7003007 | 0.75 | AOC3 (0.43) | DHFRSLC6A4SLC6A2AOC3OPRK1 | |
| SCHEMBL1198705 | 0.75 | CYP2B6 (0.34) | CYP2B6ADRB2ADRB1ADRB3SLC6A4 | |
| SCHEMBL7712823 | 0.74 | ACP3 (0.34) | CYP2B6DHFRADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2527314-B1 | Process for preparation of phenyl carbamate derivatives | BIO-PHARM SOLUTIONS CO LTD (KR) | 2017-10-04 | — | — | EP | disclosed |