Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30986310 | 0.80 | RAB9A (0.59) | ALDH1A1HTTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL263278 | 0.80 | RAB9A (0.59) | ALDH1A1HTTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL30342248 | 0.79 | KMT2A (0.64) | ALDH1A1HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL10951824 | 0.79 | KMT2A (0.64) | ALDH1A1HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL9846829 | 0.79 | HDAC3 (0.51) | ALDH1A1HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL27817210 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL29678316 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL5913136 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL1946930 | 0.78 | ALDH1A1 (0.71) | ALDH1A1HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL13652566 | 0.77 | POLB (0.59) | ALDH1A1HTTSMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925757-B1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2017-10-04 | — | — | EP | disclosed |