Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 4/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19418280 | 0.78 | CCNK (0.48) | CCNKCCNA2CDK2CDK12MEN1 | |
| SCHEMBL1539141 | 0.76 | NPC1 (0.42) | CCNKCCNA2CDK2CDK12MEN1 | |
| SCHEMBL7873766 | 0.76 | CCNK (0.47) | CCNKCCNA2CDK2CDK12MEN1 | |
| SCHEMBL27808928 | 0.74 | SLC6A4 (0.50) | SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL28787509 | 0.74 | MEN1 (0.52) | MEN1ALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL3081660 | 0.73 | SLC6A2 (0.49) | SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL21152972 | 0.71 | GPR119 (0.44) | CCNKCCNA2CDK2CDK12MEN1 | |
| SCHEMBL12733187 | 0.69 | MAOA (0.40) | ALDH1A1TSHRSLC6A2SLC6A4NSD2 | |
| SCHEMBL19418071 | 0.68 | MAOA (0.39) | ALDH1A1TSHRSLC6A2SLC6A4NSD2 | |
| SCHEMBL7153765 | 0.67 | CCNK (0.42) | CCNKCCNA2CDK2CDK12MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925757-B1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2017-10-04 | — | — | EP | disclosed |