Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19420906 | 0.84 | TLR2 (0.34) | TLR2LPAR1LPAR3SMPD1 | |
| SCHEMBL20247765 | 0.83 | SMPD1 (0.35) | LPAR3SMPD1 | |
| SCHEMBL19417963 | 0.81 | LPAR1 (0.37) | LPAR1LPAR3SMPD1 | |
| SCHEMBL20247642 | 0.79 | EPHX1 (0.33) | SMPD1 | |
| SCHEMBL19418310 | 0.78 | PTPN1 (0.36) | LPAR1LPAR3SMPD1 | |
| SCHEMBL19418243 | 0.77 | TSHR (0.49) | SMPD1 | |
| SCHEMBL19417973 | 0.77 | TSHR (0.49) | SMPD1 | |
| SCHEMBL632263 | 0.74 | TGFBR1 (0.33) | SMPD1 | |
| SCHEMBL19418271 | 0.73 | TLR2 (0.38) | TLR2 | |
| SCHEMBL15032907 | 0.69 | TLR2 (0.40) | TLR2LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225228-B1 | ACIDIC HYBRID MONOMERS AND DENTAL MATERIALS BASED THEREON | IVOCLAR VIVADENT AG (LI) | 2018-06-13 | — | — | EP | disclosed |
| EP-3225228-A1 | ACIDIC HYBRID MONOMERS AND DENTAL MATERIALS BASED THEREON | Ivoclar Vivadent AG (LI) | 2017-10-04 | — | — | EP | disclosed |