Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21572120 | 0.84 | MMP1 (0.35) | TGFBR1MMP1MMP8 | |
| SCHEMBL13488749 | 0.84 | — | — | |
| SCHEMBL19420906 | 0.76 | TLR2 (0.34) | SMPD1 | |
| SCHEMBL2319613 | 0.76 | MEN1 (0.35) | — | |
| SCHEMBL5050846 | 0.74 | MMP1 (0.38) | TGFBR1MMP1MMP8 | |
| SCHEMBL906889 | 0.73 | TSHR (0.43) | ALDH1A1 | |
| SCHEMBL27841406 | 0.73 | TGFBR1 (0.34) | TGFBR1ALDH1A1 | |
| SCHEMBL15032916 | 0.73 | TGFBR1 (0.34) | TGFBR1MMP1MMP8 | |
| SCHEMBL16362482 | 0.72 | — | — | |
| SCHEMBL14678816 | 0.72 | TPI1 (0.36) | TGFBR1MMP1MMP8PGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10478384-B2 | Dental composition | ZIMMER DENTAL, INC. (US) | 2019-11-19 | — | — | US | claimed |
| EP-2277496-B1 | Dental material containing surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2016-03-30 | — | — | EP | claimed |
| US-20140161901-A1 | DENTAL COMPOSITION | ZIMMER DENTAL, INC. (US) | 2014-06-12 | — | — | US | claimed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | claimed |
| US-8211956-B2 | Universal dental adhesion-promoter composition | IVOCLAR VIVADENT AG (LI) | 2012-07-03 | — | — | US | claimed |
| US-7851515-B2 | Hydrolysis-stable self-etching single-component dental adhesive | IVOCLAR VIVADENT AG (LI) | 2010-12-14 | — | — | US | claimed |
| EP-4094748-B1 | DENTAL MATERIALS BASED ON REDOX SYSTEMS WITH OLIGOMERIC CUMOLHYDROPEROXIDE DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2023-09-20 | — | — | EP | disclosed |
| EP-4039220-B1 | DENTAL MATERIALS ON THE BASIS OF POLYMERISABLE THIOUREA DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2022-12-28 | — | — | EP | disclosed |
| EP-4094748-A1 | DENTAL MATERIALS BASED ON REDOX SYSTEMS WITH OLIGOMERIC CUMOLHYDROPEROXIDE DERIVATIVES | Ivoclar Vivadent AG (LI) | 2022-11-30 | — | — | EP | disclosed |
| EP-4039220-A1 | DENTAL MATERIALS ON THE BASIS OF POLYMERISABLE THIOUREA DERIVATIVES | Ivoclar Vivadent AG (LI) | 2022-08-10 | — | — | EP | disclosed |
| US-11357709-B2 | Dental materials based on redox systems with low-odour cumene hydroperoxide derivatives | IVOCLAR VIVADENT AG (LI) | 2022-06-14 | — | — | US | disclosed |
| EP-3692975-B1 | DENTAL MATERIALS WITH IMPROVED SETTING | IVOCLAR VIVADENT AG (LI) | 2022-05-18 | — | — | EP | disclosed |
| US-11141356-B2 | Dental materials with improved setting behaviour | IVOCLAR VIVADENT AG (LI) | 2021-10-12 | — | — | US | disclosed |
| EP-2065363-A1 | Dental materials based on alkylenediamine-N,N,N',N'-tetraacetic acid-(meth)acrylamides | Ivoclar Vivadent AG (LI) | 2009-06-03 | — | — | EP | disclosed |
| EP-1674067-B1 | Hydrolysis-stable self-etching one-component dental adhesive | IVOCLAR VIVADENT AG (LI) | 2009-04-15 | — | — | EP | disclosed |
| EP-1674067-B1 | Hydrolysis-stable self-etching one-component dental adhesive | IVOCLAR VIVADENT AG (LI) | 2009-04-15 | — | — | EP | disclosed |
| EP-1716836-A1 | Surface-modified fillers | Ivoclar Vivadent AG (LI) | 2006-11-02 | — | — | EP | disclosed |
| US-20060247329-A1 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2006-11-02 | — | — | US | disclosed |
| EP-1674067-A1 | Hydrolysis-stable self-etching one-component dental adhesive | Ivoclar Vivadent AG (LI) | 2006-06-28 | — | — | EP | disclosed |
| US-20060130701-A1 | Hydrolysis-stable self-etching single-component dental adhesive | IVOCLAR VIVADENT AG (LI) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10478384-B2 | Dental composition | CAD, PPIP5K2, PTH1R | TGFBR1 2725/4885MMP1 4320/4885MMP8 4650/4885 |
| US-20140161901-A1 | DENTAL COMPOSITION | CAD, PPIP5K2, PTH1R | TGFBR1 2725/4885MMP1 4320/4885MMP8 4650/4885 |
| US-11141356-B2 | Dental materials with improved setting behaviour | GPX4, GPX1, TTPA | TGFBR1 4595/4885MMP1 3756/4885MMP8 2839/4885 |
| US-20060247329-A1 | Surface-modified fillers | MSR1, HRH4, OR10J3 | TGFBR1 132/4885MMP1 707/4885MMP8 680/4885 |
| US-11357709-B2 | Dental materials based on redox systems with low-odour cumene hydroperoxide derivatives | GPX4, GPX1, AOX1 | TGFBR1 1343/4885MMP1 4536/4885MMP8 4406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.