Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 7/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15032906 | 0.91 | TLR2 (0.38) | TLR2ALDH1A1LPAR3LPAR2 | |
| SCHEMBL21383587 | 0.84 | S1PR2 (0.44) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL5052645 | 0.84 | S1PR2 (0.44) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL7645968 | 0.84 | S1PR2 (0.44) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL5053958 | 0.82 | S1PR2 (0.42) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL19477967 | 0.81 | CYP2C19 (0.40) | TLR2S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL15032908 | 0.81 | TSHR (0.49) | TLR2S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL3340504 | 0.79 | TLR2 (0.42) | TLR2S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL432614 | 0.78 | S1PR2 (0.43) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL16132592 | 0.78 | THRB (0.41) | TLR2ALDH1A1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040602-B2 | Dental materials on the basis of highly acidic polymerizable bisphosphonic acids | IVOCLAR VIVADENT AG (LI) | 2015-05-26 | — | — | US | disclosed |
| US-9040602-B2 | Dental materials on the basis of highly acidic polymerizable bisphosphonic acids | IVOCLAR VIVADENT AG (LI) | 2015-05-26 | — | — | US | disclosed |
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | IVOCLAR VIVADENT AG (LI) | 2014-10-02 | — | — | US | disclosed |
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | IVOCLAR VIVADENT AG (LI) | 2014-10-02 | — | — | US | disclosed |
| WO-2013083734-A1 | DENTAL MATERIALS ON THE BASIS OF HIGHLY ACIDIC POLYMERISABLE BISPHOSPHONIC ACIDS | IVOCLAR VIVADENT AG (LI) | 2013-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | PHOSPHO1, PTK2, ITGA1 | TLR2 2605/4885S1PR2 3488/4885S1PR1 2967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.