Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | CASP3 | P42574 | 3/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19409304 | 0.90 | MAPT (0.68) | RAB9AMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL29746447 | 0.81 | MAPT (0.69) | RAB9AMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL16296882 | 0.81 | MAPT (0.69) | RAB9AMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL29249558 | 0.81 | MAPT (0.69) | RAB9AMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL30991489 | 0.81 | MAPT (0.69) | RAB9AMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL15906854 | 0.81 | RAB9A (0.68) | RAB9AMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL14571425 | 0.79 | MAPT (0.77) | RAB9AMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL29633218 | 0.79 | MAPT (0.77) | RAB9AMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL29633300 | 0.79 | CASP3 (0.77) | RAB9AMAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL16297244 | 0.79 | CASP3 (0.77) | RAB9AMAPTSMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283374-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CARCINOMA | PELLFICURE PHARMACEUTICALS, INC. | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283374-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CARCINOMA | KLK3, ACP3, NR5A1 | RAB9A 3443/4885MAPT 2538/4885SMN1; SMN2 3333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.