Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484358 | 0.91 | PDE4A (0.44) | CAMK2AGPR84FFAR1FFAR4PDE4A | |
| SCHEMBL26138070 | 0.85 | TET2 (0.46) | CAMK2AFFAR1FFAR4TET2KDM4A | |
| SCHEMBL3299289 | 0.85 | PDE4A (0.43) | CAMK2AGPR84FFAR1FFAR4GSR | |
| SCHEMBL26138083 | 0.83 | LMNA (0.50) | GPR84FFAR1FFAR4TET2KDM4A | |
| SCHEMBL1110835 | 0.83 | PDE4A (0.41) | CAMK2AGPR84FFAR1FFAR4PDE4A | |
| SCHEMBL6542236 | 0.83 | PDE4A (0.41) | CAMK2AGPR84FFAR1FFAR4PDE4A | |
| SCHEMBL9297279 | 0.83 | PDE4A (0.41) | CAMK2AGPR84FFAR1FFAR4PDE4A | |
| SCHEMBL18322325 | 0.83 | PDE4A (0.41) | CAMK2AGPR84FFAR1FFAR4PDE4A | |
| Cadaverine Tartrate SCHEMBL21314877 | 0.82 | GPR84 (0.56) | CAMK2AGPR84FFAR1FFAR4TET2 | |
| SCHEMBL6686316 | 0.81 | PDE4A (0.40) | CAMK2AGPR84FFAR1FFAR4PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3925997-B1 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | MITSUBISHI CHEM CORP (JP) | 2024-07-17 | — | — | EP | disclosed |
| US-11732087-B2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-08-22 | — | — | US | disclosed |
| EP-3925998-B1 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | MITSUBISHI CHEM CORP (JP) | 2023-06-07 | — | — | EP | disclosed |
| US-20230124462-A1 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-04-20 | — | — | US | disclosed |
| US-11560449-B2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-01-24 | — | — | US | disclosed |
| EP-3925998-A2 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | Mitsubishi Chemical Corporation (JP) | 2021-12-22 | — | — | EP | disclosed |
| EP-3925997-A2 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | Mitsubishi Chemical Corporation (JP) | 2021-12-22 | — | — | EP | disclosed |
| EP-3925996-A2 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | Mitsubishi Chemical Corporation (JP) | 2021-12-22 | — | — | EP | disclosed |
| EP-3919543-A2 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | Mitsubishi Chemical Corporation (JP) | 2021-12-08 | — | — | EP | disclosed |
| EP-3909998-A2 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | Mitsubishi Chemical Corporation (JP) | 2021-11-17 | — | — | EP | disclosed |
| EP-2366726-A2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-2366727-A2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-09-21 | — | — | EP | disclosed |
| US-8021864-B2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-09-20 | — | — | US | disclosed |
| EP-2365017-A2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-09-14 | — | — | EP | disclosed |
| US-7985566-B2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-07-26 | — | — | US | disclosed |
| US-20110009531-A1 | a dicarboxylic acid and/or a diol derived from biomass resources; capable of suppressing hydrolysis; environmentally friendly; eco-friendly | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2204396-A1 | Biomass-resource derived polyester and production process thereof | Mitsubishi Chemical Corporation (JP) | 2010-07-07 | — | — | EP | disclosed |
| EP-1882712-B1 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | MITSUBISHI CHEM CORP (JP) | 2010-04-21 | — | — | EP | disclosed |
| US-20090171037-A1 | a dicarboxylic acid and/or a diol derived from biomass resources; capable of suppressing hydrolysis; environmentally friendly; eco-friendly | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |
| EP-1882712-A1 | POLYESTER DERIVED FROM BIOMASS RESOURCES AND METHOD FOR PRODUCTION THEREOF | Mitsubishi Chemical Corporation (JP) | 2008-01-30 | — | — | EP | disclosed |