Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PGD | P52209 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299289 | 0.93 | PDE4A (0.43) | PDE4ATSHRCYP2C9PGDOR51E2 | |
| Succinic Acid SCHEMBL194222 | 0.91 | CAMK2A (0.46) | PDE4ATSHRCYP2C9PGDCAMK2A | |
| SCHEMBL1110835 | 0.91 | PDE4A (0.41) | PDE4ATSHRCYP2C9PGDOR51E2 | |
| SCHEMBL6542236 | 0.91 | PDE4A (0.41) | PDE4ATSHRCYP2C9PGDOR51E2 | |
| SCHEMBL18322325 | 0.91 | PDE4A (0.41) | PDE4ATSHRCYP2C9PGDOR51E2 | |
| SCHEMBL9297279 | 0.91 | PDE4A (0.41) | PDE4ATSHRCYP2C9PGDOR51E2 | |
| SCHEMBL6686316 | 0.89 | PDE4A (0.40) | PDE4ATSHRCYP2C9PGDOR51E2 | |
| SCHEMBL2017250 | 0.86 | PDE4A (0.52) | PDE4ATSHRCYP2C9PGDOR51E2 | |
| SCHEMBL2784989 | 0.84 | PDE4A (0.48) | PDE4ATSHRCYP2C9PGDOR51E2 | |
| SCHEMBL28394802 | 0.80 | FFAR1 (0.39) | PDE4APTPN1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239083-A1 | AEROSOL GENERATION OR SMOKING SYSTEM, OR ELECTRONIC CIGARETTE AND DEVICE THEREOF | 钟术光 | 2020-12-03 | — | — | WO | claimed |
| CN-101538261-B | Method for preparing (3R, 5S)-3, 5-O-isopropylidene-3, 5, 6-trihydroxy caproic acid hexylic acid derivative | SICHUAN IND INST ANTIBIOTICS CHINA NAT PHARMACEUTICAL GROUP CORP | 2012-11-07 | — | — | CN | claimed |
| CN-101538261-A | Method for preparing (3R, 5S)-3, 5-O-isopropylidene-3, 5, 6-trihydroxy caproic acid hexylic acid derivative | SICHUAN IND I OF ANTIBIOTICS C | 2009-09-23 | — | — | CN | claimed |
| EP-0583171-B1 | (3R,5S)-3,5,6-trihydroxyhexanoic acid derivatives and methods for their production | TAKASAGO PERFUMERY CO LTD (JP) | 1998-11-11 | — | — | EP | claimed |
| EP-0374922-B1 | Process for the production of 3,5,6-trihydroxyhexanoic acid derivative | KANEGAFUCHI CHEMICAL IND (JP) | 1995-06-28 | — | — | EP | claimed |
| EP-0583171-A2 | (3R,5S)-3,5,6-trihydroxyhexanoic acid derivatives and methods for their production | Takasago International Corporation (JP) | 1994-02-16 | — | — | EP | claimed |
| US-4983759-A | Process for the production of 3,5,6-trihydroxyhexanoic acid derivative | KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-08 | — | — | US | claimed |
| EP-0374922-A2 | Process for the production of 3,5,6-trihydroxyhexanoic acid derivative | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1990-06-27 | — | — | EP | claimed |
| US-20250127925-A1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | HERCULES CAPITAL, INC. | 2025-04-24 | — | — | US | disclosed |
| US-12076418-B2 | Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo | ENGENE, INC. (CA) | 2024-09-03 | — | — | US | disclosed |
| US-20220133907-A1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | HERCULES CAPITAL, INC. | 2022-05-05 | — | — | US | disclosed |
| EP-3970697-A1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | Engene, Inc. (CA) | 2022-03-23 | — | — | EP | disclosed |
| US-11167045-B2 | Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo | HERCULES CAPITAL, INC. | 2021-11-09 | — | — | US | disclosed |
| EP-3049473-B1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | ENGENE INC (CA) | 2021-09-22 | — | — | EP | disclosed |
| EP-1288213-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2- 6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2003-03-05 | — | — | EP | disclosed |
| EP-1288213-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2- 6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094337-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2-[6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2001-12-13 | — | — | WO | disclosed |
| EP-0374922-B1 | Process for the production of 3,5,6-trihydroxyhexanoic acid derivative | KANEGAFUCHI CHEMICAL IND (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-4983759-A | Process for the production of 3,5,6-trihydroxyhexanoic acid derivative | KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0374922-A2 | Process for the production of 3,5,6-trihydroxyhexanoic acid derivative | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250127925-A1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | CSGALNACT1, CHI3L2, LNPEP | PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885 |
| US-11167045-B2 | Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo | CSGALNACT1, CHI3L2, LNPEP | PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885 |
| US-12076418-B2 | Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo | CSGALNACT1, CHI3L2, LNPEP | PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885 |
| US-20220133907-A1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | CSGALNACT1, CHI3L2, LNPEP | PDE4A 4587/4885TSHR 4331/4885CYP2C9 4006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.