Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.83 |
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | TP53 | P04637 | 2/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | GMNN | O75496 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | HPGD | P15428 | 1/20 | 0.83 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.83 |
| ▸ | THPO | P40225 | 1/20 | 0.83 |
| ▸ | MTOR | P42345 | 1/20 | 0.83 |
| ▸ | RAB9A | P51151 | 1/20 | 0.83 |
| ▸ | BLM | P54132 | 1/20 | 0.83 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.83 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.83 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salmeterol SCHEMBL2833182 | 0.91 | ADRB2 (1.00) | ADRB2KDM4EMEN1TP53CYP3A4 | |
| Salmeterol SCHEMBL29372524 | 0.91 | ADRB2 (1.00) | ADRB2KDM4EMEN1TP53CYP3A4 | |
| Salmeterol SCHEMBL29352164 | 0.91 | ADRB2 (1.00) | ADRB2KDM4EMEN1TP53CYP3A4 | |
| Salmeterol SCHEMBL9806070 | 0.91 | ADRB2 (1.00) | ADRB2KDM4EMEN1TP53CYP3A4 | |
| Salmeterol SCHEMBL18070 | 0.91 | ADRB2 (1.00) | ADRB2KDM4EMEN1TP53CYP3A4 | |
| Salmeterol SCHEMBL19211132 | 0.91 | ADRB2 (1.00) | ADRB2KDM4EMEN1TP53CYP3A4 | |
| Salmeterol SCHEMBL17185987 | 0.90 | ADRB2 (0.98) | ADRB2KDM4EMEN1TP53CYP3A4 | |
| Salmeterol SCHEMBL9545710 | 0.90 | ADRB2 (0.98) | ADRB2KDM4EMEN1TP53CYP3A4 | |
| SCHEMBL9763391 | 0.82 | ADRB2 (0.77) | ADRB2KDM4EMEN1TP53CYP3A4 | |
| Salmeterol SCHEMBL4657562 | 0.82 | ADRB2 (0.81) | ADRB2KDM4EMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017168431-A1 | PROCESS FOR THE PREPARATION OF SALMETEROL XINAFOATE | DAVULURI RAMAMOHAN RAO (IN) | 2017-10-05 | — | — | WO | disclosed |