Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566096 | 0.90 | TLR2 (0.55) | TLR2PTPN1ECE1 | |
| SCHEMBL20759079 | 0.90 | TLR2 (0.55) | TLR2PTPN1ECE1 | |
| SCHEMBL20758846 | 0.90 | TLR2 (0.55) | TLR2PTPN1ECE1 | |
| SCHEMBL20758974 | 0.90 | TLR2 (0.55) | TLR2PTPN1ECE1 | |
| SCHEMBL30150290 | 0.89 | TLR2 (0.53) | TLR2PTPN1CTSLECE1 | |
| SCHEMBL30598967 | 0.89 | TLR2 (0.55) | TLR2PTPN1ECE1 | |
| SCHEMBL30193301 | 0.89 | TLR2 (0.53) | TLR2PTPN1CTSLECE1 | |
| SCHEMBL19423650 | 0.89 | ROCK2 (0.51) | TLR2PTPN1PRSS1PRSS2PRSS3 | |
| SCHEMBL14374768 | 0.88 | PTPN1 (0.55) | TLR2PTPN1CTSL | |
| SCHEMBL19423749 | 0.88 | TLR2 (0.55) | TLR2PTPN1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052936-A2 | ARGININE PEPTIDE ANALOGS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 1999-10-21 | — | — | WO | disclosed |