Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20705573 | 0.78 | MEN1 (0.46) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18598053 | 0.78 | ALDH1A1 (0.45) | ALDH1A1USP2HPGDNPC1RAB9A | |
| SCHEMBL20272283 | 0.78 | ALDH1A1 (0.45) | ALDH1A1USP2HPGDNPC1RAB9A | |
| SCHEMBL20272262 | 0.75 | EPHX1 (0.45) | ALDH1A1USP2HPGDNPC1RAB9A | |
| SCHEMBL21515098 | 0.67 | LPAR2 (0.67) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL13381356 | 0.67 | LPAR2 (0.67) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11586886 | 0.67 | LPAR2 (0.67) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL18467672 | 0.65 | ALDH1A1 (0.46) | ALDH1A1USP2HPGDNPC1RAB9A | |
| SCHEMBL15309134 | 0.64 | RAB9A (0.59) | ALDH1A1USP2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1380888 | 0.64 | FYN (0.62) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | UNITY BIOTECHNOLOGY, INC. | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | TP53, NQO1, SHMT2 | ALDH1A1 545/4885USP2 1179/4885HPGD 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.