Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 11/20 | 0.65 |
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | POLB | P06746 | 5/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.65 |
| ▸ | MMP2 | P08253 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.57 |
| ▸ | BCL2 | P10415 | 5/20 | 0.55 |
| ▸ | BCL2L2 | Q92843 | 5/20 | 0.55 |
| ▸ | BAD | Q92934 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894970 | 0.80 | DUSP3 (0.71) | DUSP3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14680220 | 0.79 | MAPT (1.00) | DUSP3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19425506 | 0.79 | DUSP3 (0.71) | DUSP3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19430434 | 0.75 | MAPT (1.00) | DUSP3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18598497 | 0.74 | DUSP3 (0.64) | DUSP3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL20272271 | 0.73 | MAPT (0.56) | DUSP3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4568729 | 0.73 | MAPT (0.80) | DUSP3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2683718 | 0.73 | MAPT (0.80) | DUSP3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2683719 | 0.73 | MAPT (0.80) | DUSP3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13846498 | 0.72 | MAPT (0.87) | MAPTMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | UNITY BIOTECHNOLOGY, INC. | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | TP53, NQO1, SHMT2 | DUSP3 351/4885MAPT 1762/4885MEN1 3416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.