Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13747869 | 0.80 | GPR84 (0.57) | GPR84SLC22A6MAPTGABRR1LMNA | |
| SCHEMBL16806325 | 0.80 | KDM4E (0.54) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| SCHEMBL6673903 | 0.79 | ADRA1A (0.48) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| SCHEMBL14124849 | 0.79 | ADRA1A (0.48) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| SCHEMBL31295287 | 0.79 | ADRA1A (0.48) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| SCHEMBL18541590 | 0.78 | KDM4E (0.52) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| SCHEMBL11498764 | 0.77 | ADRA1A (0.46) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| SCHEMBL28922166 | 0.76 | GPR84 (0.67) | GPR84SLC22A6FOLH1MAPTGABRR1 | |
| SCHEMBL966415 | 0.76 | GPR84 (0.74) | GPR84SLC22A6MAPTGABRR1LMNA | |
| SCHEMBL11664580 | 0.76 | KDM4E (0.54) | GPR84ADRA1AKDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017172930-A1 | PBD CONJUGATES FOR TREATING DISEASES | ENDOCYTE, INC. (US) | 2017-10-05 | — | — | WO | disclosed |