⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29537123 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL922808 | 0.97 | — | — | |
| Toluene SCHEMBL27601995 | 0.87 | ACHE (0.46) | — | |
| Formic Acid SCHEMBL28805131 | 0.87 | ADRA2A (0.41) | — | |
| SCHEMBL16826322 | 0.83 | PIK3CA (0.41) | — | |
| SCHEMBL13886044 | 0.80 | ALDH1A1 (0.56) | — | |
| SCHEMBL4228644 | 0.79 | KDM4E (0.60) | — | |
| Ethoxycarbonyl Group SCHEMBL27895449 | 0.78 | TSHR (0.36) | — | |
| SCHEMBL24167640 | 0.75 | CYP3A4 (0.56) | — | |
| SCHEMBL29887750 | 0.75 | CYP3A4 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1956 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12442027-B2 | Method of reducing aromatic nitro compounds | AMGEN INC. (US) | 2025-10-14 | — | — | US | claimed |
| CN-118126023-B | Pyrazole amide compound as well as preparation method and application thereof | 安徽中医药大学 | 2025-04-11 | — | — | CN | claimed |
| US-12269811-B2 | Synthesis of omecamtiv mecarbil | AMGEN INC. (US) | 2025-04-08 | — | — | US | claimed |
| CN-119613279-A | N-substituted benzene ring bioisostere and preparation method thereof | 上海交通大学 | 2025-03-14 | — | — | CN | claimed |
| CN-118126023-A | Pyrazole amide compound as well as preparation method and application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | claimed |
| CN-117510429-A | Compound containing methyl isoxazole structure, and preparation method and application thereof | 中国农业大学 | 2024-02-06 | — | — | CN | claimed |
| EP-4305018-A2 | SYNTHESIS OF OMECAMTIV MECARBIL | Amgen Inc. (US) | 2024-01-17 | — | — | EP | claimed |
| CN-117157274-A | Synthesis of olmesartan Mo Kabi mol | 安进股份有限公司 | 2023-12-01 | — | — | CN | claimed |
| CN-117126099-A | 3-benzyloxy methyl indole-2-carboxylic acid derivative and preparation method and application thereof | 贵州医科大学 | 2023-11-28 | — | — | CN | claimed |
| US-20230373955-A1 | SYNTHESIS OF OMECAMTIV MECARBIL | AMGEN INC. | 2023-11-23 | — | — | US | claimed |
| WO-2007083978-A1 | IMIDAZOPYRIDINE DERIVATIVES INHIBITING PROTEIN KINASE ACTIVITY, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CRYSTALGENOMICS, INC. (KR) | 2007-07-26 | — | — | WO | claimed |
| WO-2006136606-A2 | OXINDOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-28 | — | — | WO | claimed |
| US-20060293319-A1 | Oxindole derivatives | LUK KIM-CHUN | 2006-12-28 | — | — | US | claimed |
| US-20060223996-A1 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2006-10-05 | — | — | US | claimed |
| WO-2006053227-A2 | IL-12 MODULATORY COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2006-05-18 | — | — | WO | claimed |
| US-6949562-B2 | Heterocyclic compounds as ligands of the GABAA receptor | NEUROGEN CORPORATION (US) | 2005-09-27 | — | — | US | claimed |
| US-20040110778-A1 | Heterocyclic compounds as ligands of the GABAA receptor | YOHANNES DANIEL (US) | 2004-06-10 | — | — | US | claimed |
| EP-1325006-A2 | HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABA A? RECEPTOR | NEUROGEN CORPORATION (US) | 2003-07-09 | — | — | EP | claimed |
| US-20030105081-A1 | Heterocyclic compounds as ligands of the GABAA receptor | PFIZER INC | 2003-06-05 | — | — | US | claimed |
| WO-2002012442-A2 | HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR | NEUROGEN CORPORATION (US) | 2002-02-14 | — | — | WO | claimed |