Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MOK | Q9UQ07 | 2/20 | 0.34 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19430238 | 0.98 | PRMT6 (0.39) | PRMT6POLBMOKWNK1TDP1 | |
| SCHEMBL19429973 | 0.93 | PRMT6 (0.48) | PRMT6POLBMOKKDM4EALDH1A1 | |
| SCHEMBL19429853 | 0.91 | AOC3 (0.41) | POLBWNK1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19429860 | 0.90 | SMN1; SMN2 (0.44) | PRMT6KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL19430109 | 0.90 | PRMT6 (0.37) | PRMT6MOKWNK1CARM1PRMT1 | |
| SCHEMBL19429963 | 0.90 | PRMT6 (0.37) | PRMT6MOKWNK1 | |
| SCHEMBL19430299 | 0.89 | PRMT6 (0.36) | PRMT6MOKWNK1KDM4EPRMT1 | |
| SCHEMBL19430232 | 0.88 | AOC3 (0.40) | POLBWNK1TDP1KMT2A | |
| SCHEMBL19430139 | 0.88 | PRMT6 (0.41) | PRMT6MOKCARM1PRMT1 | |
| SCHEMBL19430397 | 0.84 | AOC3 (0.48) | PRMT6POLBKDM4EALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170280720-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170280720-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | PRMT1, PRMT3, PRMT5 | PRMT6 4/4885POLB 2003/4885MOK 1964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.